TAGL_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TAGL_MOUSE
• UniProt AC: P37804
• Protein Name: Transgelin
• Gene Name: Tagln
• Organism: Mus musculus (Mouse).
• Sequence Length: 201
• Subcellular Localization: Cytoplasm .
• Protein Description: Actin cross-linking/gelling protein..
• Protein Sequence: MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIVVQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPEGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLYEGKDMAAVQRTLMALGSLAVTKNDGNYRGDPNWFMKKAQEHKRDFTDSQLQEGKHVIGLQMGSNRGASQAGMTGYGRPRQIIS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MANKGPSYG ------CCCCCCCCC	26.83	-
7	Phosphorylation	-MANKGPSYGMSREV -CCCCCCCCCCCHHH	42.88	26824392
8	Phosphorylation	MANKGPSYGMSREVQ CCCCCCCCCCCHHHH	21.71	29514104
11	Phosphorylation	KGPSYGMSREVQSKI CCCCCCCCHHHHHHH	22.41	29514104
16	Phosphorylation	GMSREVQSKIEKKYD CCCHHHHHHHHHHCC	40.55	26824392
17	Acetylation	MSREVQSKIEKKYDE CCHHHHHHHHHHCCH	37.48	23236377
20	Acetylation	EVQSKIEKKYDEELE HHHHHHHHHCCHHHH	61.17	23236377
21	Acetylation	VQSKIEKKYDEELEE HHHHHHHHCCHHHHH	45.18	22733758
38	S-nitrosylation	VEWIVVQCGPDVGRP HHEEECCCCCCCCCC	6.04	21278135
38	S-nitrosocysteine	VEWIVVQCGPDVGRP HHEEECCCCCCCCCC	6.04	-
75	Acetylation	SLYPEGSKPVKVPEN HHCCCCCCCCCCCCC	65.76	23236377
85	Phosphorylation	KVPENPPSMVFKQME CCCCCCCCHHHHHHH	28.92	26824392
89	Acetylation	NPPSMVFKQMEQVAQ CCCCHHHHHHHHHHH	37.01	23236377
99	Acetylation	EQVAQFLKAAEDYGV HHHHHHHHHHHHHCC	47.00	22826441
99	Ubiquitination	EQVAQFLKAAEDYGV HHHHHHHHHHHHHCC	47.00	22790023
121	Acetylation	TVDLYEGKDMAAVQR EECCCCCCCHHHHHH	32.18	23236377
135	Phosphorylation	RTLMALGSLAVTKND HHHHHHCCEEEECCC	17.63	-
154	Acetylation	GDPNWFMKKAQEHKR CCCCHHHHHHHHHCC	35.17	23236377
164	Phosphorylation	QEHKRDFTDSQLQEG HHHCCCCCHHHHHCC	38.74	29550500
166	Phosphorylation	HKRDFTDSQLQEGKH HCCCCCHHHHHCCCE	29.72	24899341
172	Acetylation	DSQLQEGKHVIGLQM HHHHHCCCEEEEEEC	33.67	23806337
181	Phosphorylation	VIGLQMGSNRGASQA EEEEECCCCCCCHHC	20.29	26824392
183	Methylation	GLQMGSNRGASQAGM EEECCCCCCCHHCCC	43.69	24129315
186	Phosphorylation	MGSNRGASQAGMTGY CCCCCCCHHCCCCCC	24.32	26824392
191	Phosphorylation	GASQAGMTGYGRPRQ CCHHCCCCCCCCCCC	26.74	29514104
193	Phosphorylation	SQAGMTGYGRPRQII HHCCCCCCCCCCCCC	10.78	22817900
195	Methylation	AGMTGYGRPRQIIS- CCCCCCCCCCCCCC-	18.10	18959173

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TAGL_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TAGL_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TAGL_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of TAGL_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.