dbPTM

TAG53_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TAG53_CAEEL
UniProt AC	Q19981
Protein Name	Putative protein tag-53
Gene Name	tag-53
Organism	Caenorhabditis elegans.
Sequence Length	1329
Subcellular Localization	Membrane Single-pass type I membrane protein.
Protein Description
Protein Sequence	MLGNITPVSFFKTWVLKKTDVHVMISAREVFPCFIFRVFLLFQVFSRVHTLTNHANFEFEKSLSSCDKPCYNGVCLNKACVCSKGWYGSQCDHCFGRIRISDNASYISDGPLDYSPSAKCTWLIEPENSATPLKIRINSFFTECGWDYLYIYDGDSVYGKQLAALCGEQPSQEFTAASGKALVHFFSDLAINLNGFNVSYESNRCAYNCSNHGSCLNGKCDCEDGYKGLNCEYQVCQLSGKSTESPCHEGQCVDGRCECLSARVHGETCQMPVSSSVWDLIHPTNNAPTGKASHASIAIDDVVWSIGGEFFDGSSDPNNIDVYNVTSRIWSKVEVSGDMPKPRFDHTVVKYKNKLYMFGGVTKTQVRHQTTQAATNELWIFDMGSKKWAQQIHKNETIIAAPFAVAGHSAHVIRSEMFVIFGYNPLFGFMHHVQIYNFETEEWTVANTSDHVYGRFKHSAVEYTTPTGATAILVYGGSMWNNTITDSLMQFDTSTKKWSNLPQSGVQLYLHAAAYLNGLMVVVGGRGSNVTAGSKSECFSNMVQSYDVACKQWSNMSTAPVDLKRFGHSVHVIGQKLYALGGFNGKMKSDVWTLSPAKCSSATRPDECRLITDGTKCVFVDSSCVPFDPTVSYKSSFASMIKSSTPKSFDECTNTPLRLALKTCEEQTDCVSCASKSGCGWCSSGEQCLPNEQECVDGPGMLTSWEKCPQRNSVATMRPCNMENNCGSCRISPHCTWYPIDKASPCVSKEDLSPAFFLVHSRRKGKNRDPNQYQAADMSRVPRAAAFNSLAVVYEYETKSVLADRNKFLSPSHFPSFFRNATECPMPCAQRNNCSDCTDLEQCMWCPSTNRCINLEAYTLSFAYGQCHSWVTSGSGSVINRVCQAESVVCEEHKTCGECQRDPGCGWLADDSKTGLGLCIRGTSTGPLEPKPENSTWYFIDCPACQCNGHSTCFTSVGSFPPVTIEKCQSCQNHTTGAHCERCAPGFYGDARNGGVCSPCDCHHQADMCDPVSGQCFCKTKGVTGDRCDKCEAKYVGNPRNGTPCFYELAVDFIFTFKLRSDDKDNHTSEIYLYSVPYKKDTDVTFQISCESPKGNALVALNMTSSYVNGLADKSQAMMVDTICDSKGFRRVYVASDKGYPFGPDSNTTFFVRVYNFNTPVQIVVSFAQSPPINWVLFFVIFAACFIVLLVVAGLLWMIKVRIEAYRRNQRRIDEIEHMASRPFASTKMELSMLSQFSSAGGPTPLSIEPCSNYRAGVFTLAVRLPTGGKAVTPSGTSGLAVASSLCLLTPQQVGVLQAQDNGESNSGRKSNFRNLLRLTIRQRPNNND

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
103	N-linked_Glycosylation	GRIRISDNASYISDG CEEEECCCCCEECCC	24.80	17761667
197	N-linked_Glycosylation	AINLNGFNVSYESNR EECCCCEEEEECCCC	24.19	-
208	N-linked_Glycosylation	ESNRCAYNCSNHGSC CCCCCCCCCCCCCCC	12.29	-
324	N-linked_Glycosylation	PNNIDVYNVTSRIWS CCCEEEEECCCCEEC	30.36	-
395	N-linked_Glycosylation	WAQQIHKNETIIAAP HHHHHHCCCCEEECC	37.16	-
447	N-linked_Glycosylation	TEEWTVANTSDHVYG CCEEEECCCCCCCEE	35.46	-
481	N-linked_Glycosylation	VYGGSMWNNTITDSL EECCCCCCCCHHHHH	27.42	-
529	N-linked_Glycosylation	VVGGRGSNVTAGSKS EECCCCCCCCCCCHH	37.67	-
555	N-linked_Glycosylation	VACKQWSNMSTAPVD HHHHHHCCCCCCCCC	26.01	17761667
820	N-linked_Glycosylation	HFPSFFRNATECPMP HCCHHHCCCCCCCCC	46.16	-
832	N-linked_Glycosylation	PMPCAQRNNCSDCTD CCCHHHCCCCCCCCC	41.60	17761667
833	N-linked_Glycosylation	MPCAQRNNCSDCTDL CCHHHCCCCCCCCCH	28.94	-
934	N-linked_Glycosylation	PLEPKPENSTWYFID CCCCCCCCCCEEEEE	53.95	-
973	N-linked_Glycosylation	EKCQSCQNHTTGAHC HHCHHCCCCCCCCCC	38.51	-
1066	N-linked_Glycosylation	LRSDDKDNHTSEIYL ECCCCCCCCEEEEEE	46.18	-
1102	N-linked_Glycosylation	GNALVALNMTSSYVN CCEEEEEECCHHHHC	23.19	-
1147	N-linked_Glycosylation	YPFGPDSNTTFFVRV CCCCCCCCCEEEEEE	50.98	17761667

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TAG53_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TAG53_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TAG53_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of TAG53_CAEEL !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TAG53_CAEEL

Related Literatures of Post-Translational Modification

N-linked Glycosylation
Reference	PubMed
"Proteomics reveals N-linked glycoprotein diversity in Caenorhabditiselegans and suggests an atypical translocation mechanism for integralmembrane proteins."; Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T.,Taoka M., Takahashi N., Isobe T.; Mol. Cell. Proteomics 6:2100-2109(2007). Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-103; ASN-555; ASN-832 ANDASN-1147, AND MASS SPECTROMETRY.	17761667 [Abstract]