dbPTM

TAF1B_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TAF1B_DROME
UniProt AC	Q9VH20
Protein Name	TATA box-binding protein-associated factor RNA polymerase I subunit B
Gene Name	TAF1B {ECO:0000312\|FlyBase:FBgn0037792}
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	872
Subcellular Localization	Nucleus, nucleolus.
Protein Description	Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment (By similarity)..
Protein Sequence	MEEVLETMQLENMHCDVCEGTTFQEREGFYYCVECGTQKDQIRAVDITAEDNFDDTAAGRYTARTIRQKKDTEKEDEDDITSWEFYNYVLRGFLQELLNMGAKPELKLMTLQVWAAYLDSMEVAFSKSNKTGLPKLNVRALPIDARIIYNHKTFKKGKKGKKSTLTGDPNDERAKFRLWNRTKRNLDASGYRSHGGASESEGEQSLHLQWSMRARKSLKRHMPLKHLDKHSRDSKGSMSCHSLRPRVKQLHNFDRNIYCLNIIKLYVVLGIALNMVEDDIQLSDLLRFIDEEHLTKRCMLNYLPGNVAAKGKALLKDMELSKMKDKVTNKLLRVNIACMSRFINLSEYQKPNLHSLAERYILELALPPRLLKYVNSLLDLHPPTFFNAMTVHPYPRYEARTMAYILYAMKLLFGLDDLKERNISESAAKINEKLLEVGGDEAPLLFVFTEWMEFVEMRKVIVSHYNQSFARRFGVSTRTGCQVDDILAKEWKEKEQGETFGWMQGSAAMKRQHENLTHIIETMLKDHFGESSKESMEKEHIEFQPSLTPAHSYFNRILLQVSRSDGAKMKITIPDHMKVDHSARNLDPFVLETTELSQYLSQHGLKLRVEELACQEDIQNVGIFRPLTIIRGDGREYRANTEIKTETWISELKRKEKRPDFRFTQPTGTYGARYLKRITMRDARRVQLEINNPFWDVTETPSFLLKLNDNEIPLDSLSSLQTFEEGTMDPLNIPLDLPRRNLEKILNPEGSDRASDQVASDINDEPPSPETLLLQVSNFDCWLLHGYMKRIRRHDKHELRQLFPCSFRWLLETCASTIGIVWEELYEELLIVEVMYHHSIRDWSNHRNYLCIQHNTQEKDIRTLARTYKELW

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of TAF1B_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TAF1B_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TAF1B_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TAF1B_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
RPA2_DROME	RpI135	physical	24436420

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TAF1B_DROME

Related Literatures of Post-Translational Modification