TAF11_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TAF11_SCHPO
• UniProt AC: Q9US54
• Protein Name: Transcription initiation factor TFIID subunit 11
• Gene Name: taf11
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 199
• Subcellular Localization: Cytoplasm . Nucleus .
• Protein Description: Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription (By similarity)..
• Protein Sequence: MKRTGSASSVPRFQRSMSYDQSNSPTAGAHAKANTASPAAEPAPSSKEKENWNRQEENDLEEDDRDDFGTAAISKVAGKPGETDDEANEKLRTKYLLESFDEEQMQRYEVFRRANLNKTNVKKLANQILNQSVTPNVAIVISGFSKVFVGEIVELARKIQDQWGDTGPLSPDHLREAYRLSRQNRRLYPQSRHVSHLFR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MKRTGSASSVP ----CCCCCCCCCCC	29.94	21712547
6	Phosphorylation	--MKRTGSASSVPRF --CCCCCCCCCCCCH	25.10	21712547
8	Phosphorylation	MKRTGSASSVPRFQR CCCCCCCCCCCCHHH	33.30	21712547
16	Phosphorylation	SVPRFQRSMSYDQSN CCCCHHHHCCCCCCC	10.99	29996109
18	Phosphorylation	PRFQRSMSYDQSNSP CCHHHHCCCCCCCCC	27.14	29996109
19	Phosphorylation	RFQRSMSYDQSNSPT CHHHHCCCCCCCCCC	14.90	29996109
22	Phosphorylation	RSMSYDQSNSPTAGA HHCCCCCCCCCCCHH	36.06	25720772
24	Phosphorylation	MSYDQSNSPTAGAHA CCCCCCCCCCCHHHC	28.95	29996109
35	Phosphorylation	GAHAKANTASPAAEP HHHCCCCCCCCCCCC	33.11	24763107
37	Phosphorylation	HAKANTASPAAEPAP HCCCCCCCCCCCCCC	17.03	28889911
45	Phosphorylation	PAAEPAPSSKEKENW CCCCCCCCCHHHHCC	57.03	21712547
83	Phosphorylation	VAGKPGETDDEANEK HCCCCCCCCHHHHHH	55.45	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TAF11_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TAF11_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TAF11_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of TAF11_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.