dbPTM

T4S1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	T4S1_MOUSE
UniProt AC	Q64302
Protein Name	Transmembrane 4 L6 family member 1
Gene Name	Tm4sf1
Organism	Mus musculus (Mouse).
Sequence Length	202
Subcellular Localization	Membrane Multi-pass membrane protein. Colocalizes with SDCBP2 in the apical region of the cell.
Protein Description
Protein Sequence	MCYVKCARYIGYSLVWAAVFCIVANALLYFPNGETKYATEDHLSRFVWYFAGIVGGGLLMLLPAFVFIGMDEEDCCGCCGYENYGKRCSMLSSVLAALIGIVGSAYCVIVASLGLAEGPKCSDAHGVWNYTFASTEGQYLLNSSMWSKCYEPKHIVEWHVTLFSILLAFAAVEFILCLIQVINGMLGGLCGYCCSRQQQYNC

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
129	N-linked_Glycosylation	SDAHGVWNYTFASTE CCCCCCCEEEEEECC	24.46	-
142	N-linked_Glycosylation	TEGQYLLNSSMWSKC CCCCCEECCHHHHHC	29.46	19656770

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of T4S1_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of T4S1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of T4S1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of T4S1_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of T4S1_MOUSE

Related Literatures of Post-Translational Modification

N-linked Glycosylation
Reference	PubMed
"The mouse C2C12 myoblast cell surface N-linked glycoproteome:identification, glycosite occupancy, and membrane orientation."; Gundry R.L., Raginski K., Tarasova Y., Tchernyshyov I.,Bausch-Fluck D., Elliott S.T., Boheler K.R., Van Eyk J.E.,Wollscheid B.; Mol. Cell. Proteomics 8:2555-2569(2009). Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-142, AND MASSSPECTROMETRY.	19656770 [Abstract]