| UniProt ID | T4S1_HUMAN | |
|---|---|---|
| UniProt AC | P30408 | |
| Protein Name | Transmembrane 4 L6 family member 1 | |
| Gene Name | TM4SF1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 202 | |
| Subcellular Localization |
Membrane Multi-pass membrane protein. Colocalizes with SDCBP2 in the apical region of the cell (PubMed:11102519). |
|
| Protein Description | ||
| Protein Sequence | MCYGKCARCIGHSLVGLALLCIAANILLYFPNGETKYASENHLSRFVWFFSGIVGGGLLMLLPAFVFIGLEQDDCCGCCGHENCGKRCAMLSSVLAALIGIAGSGYCVIVAALGLAEGPLCLDSLGQWNYTFASTEGQYLLDTSTWSECTEPKHIVEWNVSLFSILLALGGIEFILCLIQVINGVLGGICGFCCSHQQQYDC | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 6 | S-palmitoylation | --MCYGKCARCIGHS --CCCHHHHHHHHHH | 2.22 | 29575903 | |
| 9 | S-palmitoylation | CYGKCARCIGHSLVG CCHHHHHHHHHHHHH | 2.02 | 29575903 | |
| 107 | S-palmitoylation | GIAGSGYCVIVAALG HHHCCCHHHHHHHCC | 1.60 | 29575903 | |
| 121 | S-palmitoylation | GLAEGPLCLDSLGQW CCCCCCEEECCCCCC | 4.46 | 29575903 | |
| 129 | N-linked_Glycosylation | LDSLGQWNYTFASTE ECCCCCCEEEEEECC | 20.34 | UniProtKB CARBOHYD | |
| 149 | S-palmitoylation | DTSTWSECTEPKHIV ECCCCCCCCCCHHHH | 4.33 | 29575903 | |
| 159 | N-linked_Glycosylation | PKHIVEWNVSLFSIL CHHHHHHCHHHHHHH | 10.45 | UniProtKB CARBOHYD | |
| 193 | S-palmitoylation | LGGICGFCCSHQQQY HHHHHHHHCCHHHHC | 1.09 | 29575903 | |
| 194 | S-palmitoylation | GGICGFCCSHQQQYD HHHHHHHCCHHHHCC | 3.67 | 29575903 | |
| 202 | S-palmitoylation | SHQQQYDC------- CHHHHCCC------- | 5.24 | 29575903 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of T4S1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of T4S1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of T4S1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| DNJA1_HUMAN | DNAJA1 | physical | 16169070 | |
| TBA1A_MOUSE | Tuba1a | physical | 16169070 | |
| DDR1_HUMAN | DDR1 | physical | 16169070 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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