dbPTM

T3JAM_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	T3JAM_MOUSE
UniProt AC	Q8C0G2
Protein Name	TRAF3-interacting JNK-activating modulator
Gene Name	Traf3ip3
Organism	Mus musculus (Mouse).
Sequence Length	513
Subcellular Localization	Membrane Single-pass type IV membrane protein .
Protein Description	May function as an adapter molecule that regulates TRAF3-mediated JNK activation..
Protein Sequence	MISSDSRSSPGLARWAESYEAKCERRQETRENRRRRRNETTCRQPGKVLRTQHKERLQGARQLQFLKRRNLEEEKKGQAREQGPSSKTDGGTGQVSILKESLPGANKASFPGQQETGISSEVFPALHHSSSGIQRDLGGHHASHGRAFPPQDSDIKKPHRQHRGTQTKAEEALPTIKNDASQQTNCGVAVLDKDIIQLSEYLKEALHRELILKKKMVILQDLLPALIRASDSSWKGQLNEDKLKGKLRSLENQLYTCLQKHSPWGMKKVLLEMEDQRSSYEQKAKASLQKVLEEKMCAEQQLQRAQLSLALAEQKCQEWKSQYEALKEDWRTLGDQHRELESQLHVLQSKLQGADSRDSQMSQALQLLENEHQELQTKLESLQGDGEQQSSETQDLQDQLKKSEEEKQALVSKVQQLQSLLQNQSLQLQEQEKLLKKDQGLPVWNPKLSLDEVKPEGTRKEKEEELRDQLQKETFQLQVKENELQCGQWLPVLMVVIATALAVFLANKGNLVI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MISSDSRSSPGLARW CCCCCCCCCHHHHHH	44.85	30635358
9	Phosphorylation	ISSDSRSSPGLARWA CCCCCCCCHHHHHHH	23.13	26745281
86	Phosphorylation	AREQGPSSKTDGGTG HHHCCCCCCCCCCCC	42.58	21454597
120	Phosphorylation	QQETGISSEVFPALH CCCCCCCCCHHHHHH	35.54	29472430
129	Phosphorylation	VFPALHHSSSGIQRD HHHHHHCCCCCCCCC	18.56	19060867
130	Phosphorylation	FPALHHSSSGIQRDL HHHHHCCCCCCCCCC	28.38	19060867
131	Phosphorylation	PALHHSSSGIQRDLG HHHHCCCCCCCCCCC	42.82	19060867
278	Phosphorylation	LEMEDQRSSYEQKAK HHHHHHHCHHHHHHH	31.47	-
279	Phosphorylation	EMEDQRSSYEQKAKA HHHHHHCHHHHHHHH	34.57	-
280	Phosphorylation	MEDQRSSYEQKAKAS HHHHHCHHHHHHHHH	24.51	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of T3JAM_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of T3JAM_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of T3JAM_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of T3JAM_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of T3JAM_MOUSE

Related Literatures of Post-Translational Modification