T2EB_SCHPO - dbPTM
T2EB_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID T2EB_SCHPO
UniProt AC P79011
Protein Name Transcription initiation factor IIE subunit beta
Gene Name tfa2
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 285
Subcellular Localization Nucleus .
Protein Description Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase (By similarity)..
Protein Sequence MSSLSDQLSSFKKKVANQPIYAKPQPRQPASPTPTAYLNSNDGHSSAASSPGSYSLKKKRSKTSLVYSQPADSGVGTHYLSQLHYAVEYLKERNEPKTAEEIASYLSTPLTPMLLNLLKKNNRIYYDERNETFTFKPLHNIRSGAGLLAYLDSQKTHVGMSIKELRDGWPNVTVELEELEKQGEVLLLRTRKDGVPKMVWRNDKSCDCHVDKEFQQVWHEIPIPPTLDLASELGKYGLKPTSVDPSTVKRAGHNQTPKQKKPKTRRGKITNTHLNILRDYSSMKP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
31PhosphorylationPQPRQPASPTPTAYL
CCCCCCCCCCCCEEE		35.6724763107
33PhosphorylationPRQPASPTPTAYLNS
CCCCCCCCCCEEECC		30.6721712547
35PhosphorylationQPASPTPTAYLNSND
CCCCCCCCEEECCCC		30.3421712547
46PhosphorylationNSNDGHSSAASSPGS
CCCCCCCCCCCCCCC		23.3724763107
49PhosphorylationDGHSSAASSPGSYSL
CCCCCCCCCCCCCCC		36.4624763107
50PhosphorylationGHSSAASSPGSYSLK
CCCCCCCCCCCCCCC		28.6721712547
53PhosphorylationSAASSPGSYSLKKKR
CCCCCCCCCCCCCCC		18.2221712547
256PhosphorylationKRAGHNQTPKQKKPK
HCCCCCCCCCCCCCC		37.4621712547
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of T2EB_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of T2EB_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of T2EB_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RPB2_SCHPOrpb2physical
15743411
RPB1_SCHPOrpb1physical
15743411
PROD_SCHPOSPCC70.03cgenetic
22681890
YC93_SCHPOSPCC584.03cgenetic
22681890
YNU4_SCHPOSPBC28E12.04genetic
22681890
SEH1_SCHPOseh1genetic
22681890
YD52_SCHPOSPAC6C3.02cgenetic
22681890
GET1_SCHPOget1genetic
22681890
POP2_SCHPOpop2genetic
22681890
YIT2_SCHPOSPAC105.02cgenetic
22681890
ATP11_SCHPOatp11genetic
22681890
MU172_SCHPOmsd1genetic
22681890
MUG45_SCHPOmug45genetic
22681890
PPK5_SCHPOpom2genetic
22681890
MOK11_SCHPOmok11genetic
22681890
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of T2EB_SCHPO

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Related Literatures of Post-Translational Modification

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