T22D1_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: T22D1_RAT
• UniProt AC: P62501
• Protein Name: TSC22 domain family protein 1
• Gene Name: Tsc22d1
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 143
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Description: Transcriptional repressor. Acts on the C-type natriuretic peptide (CNP) promoter..
• Protein Sequence: MKSQWCRPVAMDLGVYQLRHFSISFLSSLLGTENASVRLDNSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGSTA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
42	Phosphorylation	ASVRLDNSSGASVVA CEEEEECCCCCEEEE	29.80	26022182
43	Phosphorylation	SVRLDNSSGASVVAI EEEEECCCCCEEEEE	44.63	26022182
77	Ubiquitination	REEVEVLKEQIKELI HHHHHHHHHHHHHHH	53.39	-
86	Ubiquitination	QIKELIEKNSQLEQE HHHHHHHHCHHHHHH	55.71	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of T22D1_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of T22D1_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of T22D1_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of T22D1_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.