T184C_HUMAN - dbPTM
T184C_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID T184C_HUMAN
UniProt AC Q9NVA4
Protein Name Transmembrane protein 184C
Gene Name TMEM184C
Organism Homo sapiens (Human).
Sequence Length 438
Subcellular Localization Membrane
Multi-pass membrane protein .
Protein Description Possible tumor suppressor which may play a role in cell growth..
Protein Sequence MPCTCTWRNWRQWIRPLVAVIYLVSIVVAVPLCVWELQKLEVGIHTKAWFIAGIFLLLTIPISLWVILQHLVHYTQPELQKPIIRILWMVPIYSLDSWIALKYPGIAIYVDTCRECYEAYVIYNFMGFLTNYLTNRYPNLVLILEAKDQQKHFPPLCCCPPWAMGEVLLFRCKLGVLQYTVVRPFTTIVALICELLGIYDEGNFSFSNAWTYLVIINNMSQLFAMYCLLLFYKVLKEELSPIQPVGKFLCVKLVVFVSFWQAVVIALLVKVGVISEKHTWEWQTVEAVATGLQDFIICIEMFLAAIAHHYTFSYKPYVQEAEEGSCFDSFLAMWDVSDIRDDISEQVRHVGRTVRGHPRKKLFPEDQDQNEHTSLLSSSSQDAISIASSMPPSPMGHYQGFGHTVTPQTTPTTAKISDEILSDTIGEKKEPSDKSVDS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
3S-palmitoylation-----MPCTCTWRNW
-----CCCCCCCCCH
4.7529575903
5S-palmitoylation---MPCTCTWRNWRQ
---CCCCCCCCCHHH
4.3529575903
344PhosphorylationSDIRDDISEQVRHVG
HHHCHHHHHHHHHHC
29.0429255136
398PhosphorylationPPSPMGHYQGFGHTV
CCCCCCCCCCCCCCC
12.47-
417PhosphorylationTPTTAKISDEILSDT
CCCCCCCCHHHHHCC
28.6030266825
422PhosphorylationKISDEILSDTIGEKK
CCCHHHHHCCCCCCC
38.0729255136
424PhosphorylationSDEILSDTIGEKKEP
CHHHHHCCCCCCCCC
27.7529255136
428UbiquitinationLSDTIGEKKEPSDKS
HHCCCCCCCCCCCCC
58.1733845483
429UbiquitinationSDTIGEKKEPSDKSV
HCCCCCCCCCCCCCC
71.2423503661
432PhosphorylationIGEKKEPSDKSVDS-
CCCCCCCCCCCCCC-
59.7819581576
434UbiquitinationEKKEPSDKSVDS---
CCCCCCCCCCCC---
57.6323503661
435PhosphorylationKKEPSDKSVDS----
CCCCCCCCCCC----
35.8330177828
438PhosphorylationPSDKSVDS-------
CCCCCCCC-------
39.7133259812

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of T184C_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of T184C_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of T184C_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of T184C_HUMAN !!

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of T184C_HUMAN

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Related Literatures of Post-Translational Modification

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