dbPTM

T176A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	T176A_HUMAN
UniProt AC	Q96HP8
Protein Name	Transmembrane protein 176A
Gene Name	TMEM176A
Organism	Homo sapiens (Human).
Sequence Length	235
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description
Protein Sequence	MGTADSDEMAPEAPQHTHIDVHIHQESALAKLLLTCCSALRPRATQARGSSRLLVASWVMQIVLGILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTLLTLAAFSTAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAPTQSPEEVRRLHLCTSFMDMLKALFRTLQAMLLGVWILLLLASLTPLWLYCWRMFPTKGKRDQKEMLEVSGI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
38	Phosphorylation	KLLLTCCSALRPRAT HHHHHHHHHHCHHHH	32.27	-
80	Phosphorylation	GFFYIRDYTLLVTSG CCCCCCCEEEEEECC	6.88	28857561
81	Phosphorylation	FFYIRDYTLLVTSGA CCCCCCEEEEEECCC	20.22	28857561
85	Phosphorylation	RDYTLLVTSGAAIWT CCEEEEEECCCHHHH	22.78	28857561
86	Phosphorylation	DYTLLVTSGAAIWTG CEEEEEECCCHHHHH	20.96	28857561
92	Phosphorylation	TSGAAIWTGAVAVLA ECCCHHHHHHHHHHH	14.78	28857561
106	Phosphorylation	AGAAAFIYEKRGGTY HHHHHHHHHHCCHHH	14.67	28857561
165	O-linked_Glycosylation	DWNTPAPTQSPEEVR CCCCCCCCCCHHHHH	43.73	OGP
190	Phosphorylation	MLKALFRTLQAMLLG HHHHHHHHHHHHHHH	18.85	-
220	Phosphorylation	YCWRMFPTKGKRDQK HHHHHCCCCCCCCHH	40.96	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of T176A_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of T176A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of T176A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of T176A_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of T176A_HUMAN

Related Literatures of Post-Translational Modification