T161B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: T161B_HUMAN
• UniProt AC: Q8NDZ6
• Protein Name: Transmembrane protein 161B
• Gene Name: TMEM161B
• Organism: Homo sapiens (Human).
• Sequence Length: 487
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MGVIGIQLVVTMVMASVMQKIIPHYSLARWLLCNGSLRWYQHPTEEELRILAGKQQKGKTKKDRKYNGHIESKPLTIPKDIDLHLETKSVTEVDTLALHYFPEYQWLVDFTVAATVVYLVTEVYYNFMKPTQEMNISLVWCLLVLSFAIKVLFSLTTHYFKVEDGGERSVCVTFGFFFFVKAMAVLIVTENYLEFGLETGFTNFSDSAMQFLEKQGLESQSPVSKLTFKFFLAIFCSFIGAFLTFPGLRLAQMHLDALNLATEKITQTLLHINFLAPLFMVLLWVKPITKDYIMNPPLGKESIPLMTEATFDTLRLWLIILLCALRLAMMRSHLQAYLNLAQKCVDQMKKEAGRISTVELQKMVARVFYYLCVIALQYVAPLVMLLHTTLLLKTLGNHSWGIYPESISTLPVDNSLLSNSVYSELPSAEGKMKVTVTQITVALSSLKNIFTPLLFRGLLSFLTWWIAACLFSTSLFGLFYHQYLTVA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	IGIQLVVTMVMASVM CHHHHHHHHHHHHHH	9.14	24043423
16	Phosphorylation	VVTMVMASVMQKIIP HHHHHHHHHHHHHCC	10.46	24719451
25	Phosphorylation	MQKIIPHYSLARWLL HHHHCCCCHHHHHHH	10.46	24719451
26	Phosphorylation	QKIIPHYSLARWLLC HHHCCCCHHHHHHHH	16.72	24719451
34	N-linked_Glycosylation	LARWLLCNGSLRWYQ HHHHHHHCCCCEECC	42.95	UniProtKB CARBOHYD
36	Phosphorylation	RWLLCNGSLRWYQHP HHHHHCCCCEECCCC	10.77	22985185
72	Phosphorylation	KYNGHIESKPLTIPK CCCCCCCCCCCCCCC	38.68	24719451
73	Ubiquitination	YNGHIESKPLTIPKD CCCCCCCCCCCCCCC	31.12	-
79	Ubiquitination	SKPLTIPKDIDLHLE CCCCCCCCCEEEEEE	64.56	-
135	N-linked_Glycosylation	MKPTQEMNISLVWCL CCCCHHCCHHHHHHH	21.68	UniProtKB CARBOHYD
203	N-linked_Glycosylation	GLETGFTNFSDSAMQ CCCCCCCCCCHHHHH	31.96	UniProtKB CARBOHYD
310	Phosphorylation	IPLMTEATFDTLRLW CCCCCCCCHHHHHHH	18.80	-
313	Phosphorylation	MTEATFDTLRLWLII CCCCCHHHHHHHHHH	15.02	-
357	Phosphorylation	KEAGRISTVELQKMV HHHCCCCHHHHHHHH	18.67	-
388	Phosphorylation	PLVMLLHTTLLLKTL HHHHHHHHHHHHHHH	21.07	28387310
389	Phosphorylation	LVMLLHTTLLLKTLG HHHHHHHHHHHHHHC	12.50	28387310
427	Phosphorylation	SVYSELPSAEGKMKV CHHHCCCCCCCCCEE	52.13	28387310
444	Phosphorylation	TQITVALSSLKNIFT HHHHHHHHHHHHCCH	24.72	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of T161B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of T161B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of T161B_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of T161B_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.