T121B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: T121B_HUMAN
• UniProt AC: Q9BXQ6
• Protein Name: Transmembrane protein 121B {ECO:0000305}
• Gene Name: TMEM121B {ECO:0000312|HGNC:HGNC:1844}
• Organism: Homo sapiens (Human).
• Sequence Length: 578
• Protein Sequence: MRPALGHPRSVSSASGSFPPPPAAARLQPLFLRGGSFRGRRGSGDSSTSTSTSRGGGGGRRGGGGGSPSSSTGAEREDDDESLSVSKPLVPNAALLGPPAQVGAPAGPAPVAFSSSAATSSSTSTPTSSCSMTAADFGGGAAAGAVGGPGSRSAGGAGGTGTGSGASCCPCCCCCGCPDRPGRRGRRRGCAPSPRCRWGYQALSVVLLLAQGGLLDLYLIAVTDLYWCSWIATDLVVVVGWAIFFAKNSRGRRGGAASGAHNHHLHHHHAAPPLHLPAPSAATAGAKARGARGGAGGAGGGLGAAAAAGEFAFAYLAWLIYSIAFTPKVVLILGTSILDLIELRAPFGTTGFRLTMALSVPLLYSLVRAISEAGAPPGSAGPLLLQPQRHRAAGCFLGTCLDLLDSFTLVELMLEGRVPLPAHLRYLLIAVYFLTLASPVLWLYELNAAAAAAASWGQASGPGSCSRLLRLLGGCLVDVPLLALRCLLVVSYQQPLSIFMLKNLFFLGCRGLEALEGCWDRGNRASPSRARGGYGAPPSAPPPPPPPPQGGSQLGHCISENEGGAHGYVNTLAVASQN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Phosphorylation	LGHPRSVSSASGSFP CCCCCCCCCCCCCCC		30576142
13	Phosphorylation	GHPRSVSSASGSFPP CCCCCCCCCCCCCCC		30576142
15	Phosphorylation	PRSVSSASGSFPPPP CCCCCCCCCCCCCCC		30576142
17	Phosphorylation	SVSSASGSFPPPPAA CCCCCCCCCCCCCHH		-
43	Phosphorylation	SFRGRRGSGDSSTST CCCCCCCCCCCCCCC		-
70	Phosphorylation	GGGGSPSSSTGAERE CCCCCCCCCCCCCCC		22210691
82	Phosphorylation	EREDDDESLSVSKPL CCCCCCCCCCCCCCC		22210691
84	Phosphorylation	EDDDESLSVSKPLVP CCCCCCCCCCCCCCC		24719451
86	O-linked_Glycosylation	DDESLSVSKPLVPNA CCCCCCCCCCCCCCC		30379171
86	Phosphorylation	DDESLSVSKPLVPNA CCCCCCCCCCCCCCC		22210691
160	Phosphorylation	SAGGAGGTGTGSGAS CCCCCCCCCCCCCCC		22210691
167	Phosphorylation	TGTGSGASCCPCCCC CCCCCCCCCCCCCCC		22210691
359	Phosphorylation	FRLTMALSVPLLYSL HHHHHHHHHHHHHHH		23663014
364	Phosphorylation	ALSVPLLYSLVRAIS HHHHHHHHHHHHHHH		23663014
365	Phosphorylation	LSVPLLYSLVRAISE HHHHHHHHHHHHHHH		23663014
552	Phosphorylation	PPPPQGGSQLGHCIS CCCCCCCCCCCCEEE		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of T121B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of T121B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of T121B_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of T121B_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.