T106A_HUMAN - dbPTM
T106A_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID T106A_HUMAN
UniProt AC Q96A25
Protein Name Transmembrane protein 106A
Gene Name TMEM106A
Organism Homo sapiens (Human).
Sequence Length 262
Subcellular Localization Membrane
Single-pass membrane protein .
Protein Description
Protein Sequence MGKTFSQLGSWREDENKSILSSKPAIGSKAVNYSSTGSSKSFCSCVPCEGTADASFVTCPTCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAVLICLVTSSFIVFFLFPRSVIVQPAGLNSSTVAFDEADIYLNITNILNISNGNYYPIMVTQLTLEVLHLSLVVGQVSNNLLLHIGPLASEQMFYAVATKIRDENTYKICTWLEIKVHHVLLHIQGTLTCSYLSHSEQLVFQSYEYVDCRGNASVPHQLTPHPP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
10PhosphorylationKTFSQLGSWREDENK
CCHHHCCCCCCCCCC
31.3920068231
18PhosphorylationWREDENKSILSSKPA
CCCCCCCCHHCCCCC
40.1022210691
22PhosphorylationENKSILSSKPAIGSK
CCCCHHCCCCCCCCC
38.9322210691
23UbiquitinationNKSILSSKPAIGSKA
CCCHHCCCCCCCCCC
34.78-
26UbiquitinationILSSKPAIGSKAVNY
HHCCCCCCCCCCEEC
9.68-
29UbiquitinationSKPAIGSKAVNYSST
CCCCCCCCCEECCCC
51.66-
34PhosphorylationGSKAVNYSSTGSSKS
CCCCEECCCCCCCCC
19.0728857561
35PhosphorylationSKAVNYSSTGSSKSF
CCCEECCCCCCCCCC
26.8228348404
36PhosphorylationKAVNYSSTGSSKSFC
CCEECCCCCCCCCCE
34.8328857561
38PhosphorylationVNYSSTGSSKSFCSC
EECCCCCCCCCCEEE
34.3828857561
39PhosphorylationNYSSTGSSKSFCSCV
ECCCCCCCCCCEEEE
33.3928857561
74UbiquitinationKIPQELEKQLVALIP
CCCHHHHHHHHHEEE
62.65-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of T106A_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of T106A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of T106A_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of T106A_HUMAN !!

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of T106A_HUMAN

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Related Literatures of Post-Translational Modification

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