dbPTM

SYVM1_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SYVM1_ARATH
UniProt AC	P93736
Protein Name	Valine--tRNA ligase, mitochondrial 1 {ECO:0000305}
Gene Name	TWN2 {ECO:0000303\|PubMed:9207094}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	1108
Subcellular Localization	Mitochondrion . Cytoplasm, cytosol .
Protein Description	Required for embryo development and seed viability..
Protein Sequence	MSLLFLRRAKPLFVSCCSATHSRSSFLSPTLTNQLVRSFHGSRTMSESEKKILTEEELERKKKKEEKAKEKELKKQKALEKERLAELKAKQAKDGTNVPKKSAKKSSKRDASEENPEDFVDPETPLGERKRLSSQMAKQYSPATVEKSWYAWWEKSDLFKADAKSSKPPFVIVLPPPNVTGALHIGHALTSAIEDTIIRWKRMSGYNALWVPGVDHAGIATQVVVEKKIMRDRGMTRHDVGREEFVKEVWKWKNQYGGTILTQLRRLGASLDWSRECFTMDEQRSKAVTEAFVRLYKEGLIYRDIRLVNWDCILRTAISDVEVEYIDIKEKTLLKVPGYEKPVEFGLLTSFAYPLEGGLGEVIVATTRVETMLGDTAIAIHPDDARYKHLHGKFAVHPFNGRKLPIICDGILVDPNFGTGCVKITPAHDPNDCEVGKRHKLEFINIFTDDGKINTNGGSDFAGMPRFAAREAVVEALQKQGLYRGAKNNEMRLGLCSRTNDVIEPMIKPQWYVNCSMIGKEALDVAITDENKKLEFVPKQYTAEWRRWLENIRDWCISRQLWWGHRIPAWYATLEEDQLKEVGAYSDHWVVARTEDDAREEAAQKFLGKKFELTRDPDVLDTWFSSGLFPLSVLGWPDVTDDFKAFYPTSVLETGHDILFFWVARMVMMGMKLGGEVPFSKVYFHPMIRDAHGRKMSKSLGNVIDPLEVINGVTLEGLHKRLEEGNLDPKEVIVAKEGQVKDFPNGIPECGTDALRFALVSYTAQSDKINLDILRVVGYRQWCNKLWNAVRFAMMKLGDGYTPPQTLSPETMPFSCQWILSVLNKAISKTVVSLDAFEFSDAANTIYAWWQYQFCDVYIEAIKPYFAGDNPTFASERAHAQHALWISLETGLRLLHPFMPFVTEELWQRLPAPKDTERKASIMICDYPSAIENWSNEKVESEMDTVLATVKCMRALRAGLLEKQKNERLPAFALCENNVTSEIVKSHELEIRTLANLSSLEVVSKGQHAAPPGSSVETVNENLKVYLEVDGAINTEAEQEKIRNKIGELQKQKEKLQKMMSVSTYEEKVPANIKEDNANKLAKILQEFDFFEKESARLAAETSNSGNQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
136	Sulfoxidation	RKRLSSQMAKQYSPA HHHHHHHHHHHCCCC	25693801
1017	Phosphorylation	APPGSSVETVNENLK CCCCCCCCCCCCCEE	23572148
1061	Phosphorylation	EKLQKMMSVSTYEEK HHHHHHHCCCCCCCC	19880383
1105	Phosphorylation	LAAETSNSGNQ---- HHHHCCCCCCC----	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SYVM1_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SYVM1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SYVM1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SYVM1_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SYVM1_ARATH

Related Literatures of Post-Translational Modification