SYRM_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SYRM_MOUSE
• UniProt AC: Q3U186
• Protein Name: Probable arginine--tRNA ligase, mitochondrial
• Gene Name: Rars2
• Organism: Mus musculus (Mouse).
• Sequence Length: 578
• Subcellular Localization: Mitochondrion matrix.
• Protein Sequence: MACGFRRSIACQLSRVLALPPESLIKSISAVPVSKKEEVADFQLSVDSLLEDNNHKSQVDTQDQARRLAEKLKCDTVVTAISAGPRTLNFKINRELLTKAVLQQVTEDGCKYGLKSELFSDLPKKRIVVEFSSPNIAKKFHVGHLRSTIIGNFIANLKEALGHQVTRINYIGDWGMQFGLLGTGFQLFGYEEKLQTNPLQHLFDVYVQVNKEATDDKNVTKLAHEFFHRLEMGDTQALSLWQRFRDLSIEEYTQIYKRLGIYFDEYSGESFYREKSQDVLKLLDSKGLLQKTAEGNVVVDLSGTGDLSSVCTVMRSDGTSLYATRDLAAAIHRMDKYNFDTMIYVADKGQRRHFQQVFQMLKIMGYDWAERCQHVPFGIVKGMKTRRGGVTFLEDVLNEVQSRMLQNMASIKTTKQLENPQETAERVGLAAVIIQDFRGTLLSDYQFSWDRVFQSRGDTGVFLQYTHARLCSLEETFGCGYLNDSNVACLQEPQSVSILQHLLRFDEVLYLSSQDLQPKHIVSYLLTLSHLAAVAHKTLQVKDSPPDVAGARLHLFKAVRSVLANGMKLLGITPVCRM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
74	Glutathionylation	RLAEKLKCDTVVTAI HHHHHCCCCEEEEEH	8.43	24333276
111	Acetylation	QVTEDGCKYGLKSEL HHCCCCCCCCCCHHH	48.13	23576753
132	Phosphorylation	KRIVVEFSSPNIAKK CEEEEEECCCCHHHH	31.23	28066266
133	Phosphorylation	RIVVEFSSPNIAKKF EEEEEECCCCHHHHC	27.56	28066266
413	Phosphorylation	QNMASIKTTKQLENP HHHHHHCCHHHCCCH	37.24	30635358
414	Phosphorylation	NMASIKTTKQLENPQ HHHHHCCHHHCCCHH	16.28	30635358
423	Phosphorylation	QLENPQETAERVGLA HCCCHHHHHHHHCCE	28.68	30635358
440	Phosphorylation	IIQDFRGTLLSDYQF HECCCCCCHHCCCCC	21.92	-
557	Acetylation	GARLHLFKAVRSVLA HHHHHHHHHHHHHHH	52.94	23864654
568	Acetylation	SVLANGMKLLGITPV HHHHHCHHHCCCCCC	41.79	23576753
576	S-nitrosocysteine	LLGITPVCRM----- HCCCCCCCCC-----	3.01	-
576	S-nitrosylation	LLGITPVCRM----- HCCCCCCCCC-----	3.01	21278135

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SYRM_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SYRM_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SYRM_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SYRM_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.