dbPTM

SYNPR_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SYNPR_HUMAN
UniProt AC	Q8TBG9
Protein Name	Synaptoporin
Gene Name	SYNPR
Organism	Homo sapiens (Human).
Sequence Length	265
Subcellular Localization	Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane Multi-pass membrane protein. Cell junction, synapse, synaptosome.
Protein Description	Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity)..
Protein Sequence	MCMVIFAPLFAIFAFATCGGYSGGLRLSVDCVNKTESNLSIDIAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPSNKCMAIHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWHSSGQRYLSDPMEKHSSSYNQGGYNQDSYGSSSGYSQQASLGPTSDEFGQQPTGPTSFTNQI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
33	N-linked_Glycosylation	RLSVDCVNKTESNLS EEEEECCCCCCCCEE	52.44	UniProtKB CARBOHYD
38	N-linked_Glycosylation	CVNKTESNLSIDIAF CCCCCCCCEEEEEEE	31.41	UniProtKB CARBOHYD
146	Phosphorylation	LSDVKVATDPKEVLL CCCCEECCCHHHHHH	56.68	26546556
156	Phosphorylation	KEVLLLMSACKQPSN HHHHHHHHHCCCCCC	30.40	26546556
159	Ubiquitination	LLLMSACKQPSNKCM HHHHHHCCCCCCCEE	66.03	-
162	Phosphorylation	MSACKQPSNKCMAIH HHHCCCCCCCEEECC	46.56	-
174	Phosphorylation	AIHSPVMSSLNTSVV ECCCHHHHHCCHHHH	31.72	-
175	Phosphorylation	IHSPVMSSLNTSVVF CCCHHHHHCCHHHHH	13.93	-
212	Phosphorylation	SSGQRYLSDPMEKHS CCCCEECCCCHHHCC	30.63	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SYNPR_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SYNPR_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SYNPR_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
LNP_HUMAN	KIAA1715	physical	26186194
LNP_HUMAN	KIAA1715	physical	28514442

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SYNPR_HUMAN

Related Literatures of Post-Translational Modification