dbPTM

SYKC_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SYKC_SCHPO
UniProt AC	Q9UUE6
Protein Name	Lysine--tRNA ligase, cytoplasmic
Gene Name	krs1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	591
Subcellular Localization	Cytoplasm.
Protein Description
Protein Sequence	MSEEQVNGVTQAVKALVLDPVTGEQVSKTELKKREKQRARELAKAKKQAEKAASAPVAAPKSSSKKEEDLDPSQYFENRSRTIMELRQTKDPNPYPHKFQVTITLPEFIAKYEGLARGETKPEVEVAVAGRVLGLRTAGNKLRFYEIHADGKKLQVMCQAQDADTVDFAAQHEHLRRGDIIGIRGYPGRSNPKGRADGELSIFARQCVLLSPCLRMLPKEHYGLKDLEIRHRQRYLDLIMNRSTRDRFVMRSRIIQYIRHFFDSRDFMEVETPMMNMIAGGATAKPFVTHHNDLDMDLYMRIAPELYLKMLVVGGLDRVYEIGRQFRNEGADLTHNPEFTSIEFYQAYADYYDLMDTTEELLSGLVKDLTGSYKVPYHPEGPEGPKWELDFSRPWRRINMIEYLEEKLNTKFPPGDQLHTPEANAFLRDLCAKHGVECAPPQTCSRLLDKLVGEFIESECINPTFIIGHPQMMSPLAKYHRSDAGLCERFEAFVATKEICNAYTELNDIFDQRARFEEQARQKAQGDDEAQIIDENFCTALEYGLPPTGGWGMGVDRLVMFLTDSNTIREVLLFPHMKPEVQAAEPTVVKE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSEEQVNGV ------CCHHHHHHH	50.25	24763107
10	Phosphorylation	EEQVNGVTQAVKALV HHHHHHHHHHHHHHH	16.53	19547744
62	Phosphorylation	APVAAPKSSSKKEED CCCCCCCCCCCCHHH	38.49	25720772
63	Phosphorylation	PVAAPKSSSKKEEDL CCCCCCCCCCCHHHC	52.91	25720772
64	Phosphorylation	VAAPKSSSKKEEDLD CCCCCCCCCCHHHCC	55.63	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SYKC_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SYKC_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SYKC_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SYKC_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SYKC_SCHPO

Related Literatures of Post-Translational Modification