SYFA_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SYFA_SCHPO
• UniProt AC: O42870
• Protein Name: Phenylalanine--tRNA ligase alpha subunit
• Gene Name: frs2
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 499
• Subcellular Localization: Cytoplasm .
• Protein Sequence: MSKLEALQVFLLEKLNEKNEIPNTSHLEFDGKKLGPQEAQSAILSLAAKNMIEFSRHEIEIYNLTAEGENICANGSHEAKVYNEICASMSGLNIGELKKKLGNSAGIGQGRAFKLGWIKKDGDKLVKNTDSITDETPKVLSEIKEHGTISDSKTLTDLKKRKLVERNKIMYFSLRKGPNFSLQIEKLNTDLTAEMITSRSWESAKFKSYNFAAEGIPPAGGCLHPLMKVREEFRKFFFELGFEEMPTNNFVESGFWNFDALFVPQQHSARDAQDTFFLKVPASTDKLPDPEYVARVKATHENGGETKGIGYRAPFSLEETRKLVLRTHTTAVSANMLYKLAQNGFHPAKYFSIDRVFRNETVDATHLAEFHQVEGVICDRNITLGDLIGFLEVFFGKMNVKNLRFKPAYNPYTEPSLEVFSYHEKLGKWVEVGNSGMFRPEMLEPMGLPKDVRCLGFGLSLERPTMIKYGVADIRQLIGPKVNLDLIEASPAVRLDKEE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
192	Phosphorylation	EKLNTDLTAEMITSR EECCCCCCHHHHHCC	24.31	21712547
198	Phosphorylation	LTAEMITSRSWESAK CCHHHHHCCCHHHHC	17.25	24763107
203	Phosphorylation	ITSRSWESAKFKSYN HHCCCHHHHCCEECC	30.42	21712547
292	Phosphorylation	DKLPDPEYVARVKAT CCCCCHHHEEEEEEE	12.56	27738172

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SYFA_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SYFA_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SYFA_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of SYFA_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.