SYF2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SYF2_SCHPO
• UniProt AC: O59733
• Protein Name: Pre-mRNA-splicing factor syf2
• Gene Name: syf2
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 229
• Subcellular Localization: Nucleus.
• Protein Description: Involved in pre-mRNA splicing..
• Protein Sequence: MDSPSHSREARVEKLKKIREQMRKSSHENRKEVVQEHSRMRIDPALERRLERKRMEAEEELAKIETEEEGGDFERRRAWDWTIEESEKWDQRLRKKKQTIQNVAFSDYHSQASKDYNRGIRDLKPDYEKYDKDKKEEKSKSRSVALYDEAERLDWVSNKPDKEHVERLVESIKKQDQRRLKNTKRRGTDEEDHITFINERNRKFNLKLQRFYSKYTKDIKEDLERGTAL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MDSPSHSREA -----CCCCCCCHHH	27.31	21712547
5	Phosphorylation	---MDSPSHSREARV ---CCCCCCCHHHHH	37.74	29996109
7	Phosphorylation	-MDSPSHSREARVEK -CCCCCCCHHHHHHH	35.83	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SYF2_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SYF2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SYF2_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of SYF2_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.