SWET1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SWET1_HUMAN
• UniProt AC: Q9BRV3
• Protein Name: Sugar transporter SWEET1
• Gene Name: SLC50A1
• Organism: Homo sapiens (Human).
• Sequence Length: 221
• Subcellular Localization: Golgi apparatus membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . May also localize to the endoplasmic reticulum..
• Protein Description: Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1..
• Protein Sequence: MEAGGFLDSLIYGACVVFTLGMFSAGLSDLRHMRMTRSVDNVQFLPFLTTEVNNLGWLSYGALKGDGILIVVNTVGAALQTLYILAYLHYCPRKRVVLLQTATLLGVLLLGYGYFWLLVPNPEARLQQLGLFCSVFTISMYLSPLADLAKVIQTKSTQCLSYPLTIATLLTSASWCLYGFRLRDPYIMVSNFPGIVTSFIRFWLFWKYPQEQDRNYWLLQT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
19	Phosphorylation	YGACVVFTLGMFSAG HHHHHHHHHHHHHCC	15.70	-
28	Phosphorylation	GMFSAGLSDLRHMRM HHHHCCHHHHHHHCC	33.41	24719451
134	Phosphorylation	QQLGLFCSVFTISMY HHHHHHHHHHHHHHH	16.97	-
154	Phosphorylation	DLAKVIQTKSTQCLS HHHHHHCCCCCHHHC	18.81	-
216	Phosphorylation	PQEQDRNYWLLQT-- CHHHCCCCEEEEC--	9.79	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SWET1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SWET1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SWET1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of SWET1_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.