SWAHC_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SWAHC_MOUSE
• UniProt AC: Q8C0J6
• Protein Name: Ankyrin repeat domain-containing protein SOWAHC
• Gene Name: Sowahc
• Organism: Mus musculus (Mouse).
• Sequence Length: 512
• Protein Sequence: MEGSLELSSEAILRFLAERGGRAGHSELVQHFRDVLGGQREQRTRARERFKELVNAVATVRTDPADGTKYVHLKKRFCTGDSPPLEAKLPREPPRIEVTEEPQVPDLAAEPCEGSQLQEANPQLSLGLGGEVSDQEPPAPAQGGAQGKDSPPQEVEAVSWASGPGSSENLKLPPQGEAEGGSSPSGPNTPRSARQNFRDLVLGSSPQLKRSVGPGDGNAGGRSRGGGDSDTASLASSSAEEESSVGASVTLDPLDHAWMLSASEGKWDSLEGLLTCEPGLLSKRDFITGFTCLHWAAKHGRQELLAMLVNFATKHQLPVNINAKSSGGYTALHLAAMHGHVEVVKLLVGAYDADVDIRDYSGRKASQYLSESIAEEIKNLVGALDEDDGDSPAARGGGRWRLSKVLPSHITHKLSPVVEDGAELHHHVPEGWTGGSKAKDSGRKASGSSSGRMKPRLNKIRFRTQIIHTTPSFRDAKPTLEEGEEEEEEEEERSLRGYSSSFKLRPKSNVFG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
79	Phosphorylation	HLKKRFCTGDSPPLE EEECEECCCCCCCHH	41.11	22324799
82	Phosphorylation	KRFCTGDSPPLEAKL CEECCCCCCCHHHCC	29.75	25521595
125	Phosphorylation	QEANPQLSLGLGGEV HHHCCCCCCCCCCCC	18.36	-
150	Phosphorylation	GGAQGKDSPPQEVEA CCCCCCCCCHHHEEE	41.80	28973931
159	Phosphorylation	PQEVEAVSWASGPGS HHHEEEEEECCCCCC	24.79	30635358
162	Phosphorylation	VEAVSWASGPGSSEN EEEEEECCCCCCCCC	38.98	30635358
166	Phosphorylation	SWASGPGSSENLKLP EECCCCCCCCCCCCC	37.30	25521595
167	Phosphorylation	WASGPGSSENLKLPP ECCCCCCCCCCCCCC	36.10	26643407
189	Phosphorylation	SSPSGPNTPRSARQN CCCCCCCCCCHHHHH	24.18	25338131
204	Phosphorylation	FRDLVLGSSPQLKRS HHHHHHCCCCCHHCC	34.38	22942356
205	Phosphorylation	RDLVLGSSPQLKRSV HHHHHCCCCCHHCCC	18.18	25521595
223	Phosphorylation	DGNAGGRSRGGGDSD CCCCCCCCCCCCCCC	38.25	51460165
329	Phosphorylation	NAKSSGGYTALHLAA ECCCCCCHHHHHHHH	7.74	-
391	Phosphorylation	LDEDDGDSPAARGGG CCCCCCCCCCCCCCC	23.20	26824392
395	Methylation	DGDSPAARGGGRWRL CCCCCCCCCCCCCEE	46.53	24129315
408	Phosphorylation	RLSKVLPSHITHKLS EECCCCCCHHHHCCC	24.30	26643407
411	Phosphorylation	KVLPSHITHKLSPVV CCCCCHHHHCCCCCC	13.92	108495761
413	Acetylation	LPSHITHKLSPVVED CCCHHHHCCCCCCCC	41.85	15616793
415	Phosphorylation	SHITHKLSPVVEDGA CHHHHCCCCCCCCCC	22.05	26643407
446	Phosphorylation	KDSGRKASGSSSGRM CCCCCCCCCCCCCCC	42.09	21183079
450	Phosphorylation	RKASGSSSGRMKPRL CCCCCCCCCCCCCCC	31.92	21183079
472	Phosphorylation	QIIHTTPSFRDAKPT EEEECCCCHHHCCCC	30.71	24719451
498	Phosphorylation	EERSLRGYSSSFKLR HHHHHCCCCCCCCCC	10.03	29514104
500	Phosphorylation	RSLRGYSSSFKLRPK HHHCCCCCCCCCCCC	31.17	29176673
501	Phosphorylation	SLRGYSSSFKLRPKS HHCCCCCCCCCCCCC	22.06	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SWAHC_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SWAHC_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SWAHC_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SWAHC_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.