dbPTM

SVOPL_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SVOPL_HUMAN
UniProt AC	Q8N434
Protein Name	Putative transporter SVOPL
Gene Name	SVOPL
Organism	Homo sapiens (Human).
Sequence Length	492
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description
Protein Sequence	MATKPTEPVTILSLRKLSLGTAEPQVKEPKTFTVEDAVETIGFGRFHIALFLIMGSTGVVEAMEIMLIAVVSPVIRCEWQLENWQVALVTTMVFFGYMVFSILFGLLADRYGRWKILLISFLWGAYFSLLTSFAPSYIWFVFLRTMVGCGVSGHSQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLLIIGLASVIIPTIGWRWLIRVASIPGIILIVAFKFIPESARFNVSTGNTRAALATLERVAKMNRSVMPEGKLVEPVLEKRGRFADLLDAKYLRTTLQIWVIWLGISFAYYGVILASAELLERDLVCGSKSDSAVVVTGGDSGESQSPCYCHMFAPSDYRTMIISTIGEIALNPLNILGINFLGRRLSLSITMGCTALFFLLLNICTSSAGLIGFLFMLRALVAANFNTVYIYTAEVYPTTMRALGMGTSGSLCRIGAMVAPFISQVLMSASILGALCLFSSVCVVCAISAFTLPIETKGRALQQIK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MATKPTEPVT -----CCCCCCCCEE	35.94	26503514
6	Phosphorylation	--MATKPTEPVTILS --CCCCCCCCEEEEE	55.25	26503514
105	Ubiquitination	MVFSILFGLLADRYG HHHHHHHHHHHHHHC	19.14	21963094
113	Ubiquitination	LLADRYGRWKILLIS HHHHHHCHHHHHHHH	23.68	21963094
166	Ubiquitination	IIKTEFLPTKYRGYM EEEEEECCCCCCCCC	31.97	21963094
174	Ubiquitination	TKYRGYMLPLSQVFW CCCCCCCCCHHHHHH	2.65	21963094
257	Ubiquitination	RSVMPEGKLVEPVLE CCCCCCCCCCHHHHH	47.93	21963094
265	Ubiquitination	LVEPVLEKRGRFADL CCHHHHHHCCCHHHH	56.86	21963094

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SVOPL_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SVOPL_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SVOPL_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SVOPL_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SVOPL_HUMAN

Related Literatures of Post-Translational Modification