SURF6_MOUSE - dbPTM
SURF6_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SURF6_MOUSE
UniProt AC P70279
Protein Name Surfeit locus protein 6
Gene Name Surf6
Organism Mus musculus (Mouse).
Sequence Length 355
Subcellular Localization Nucleus, nucleoplasm . Granular component of the nucleolus.
Protein Description Binds to both DNA and RNA in vitro, with a stronger binding capacity for RNA. May represent a nucleolar constitutive protein involved in ribosomal biosynthesis or assembly..
Protein Sequence MASLLAKDTYLQDLAKKICAQPGPERQRSTWGVRTKGSEAAGAPKKKRKKTQKKSPEQEQKAMDHKTKALGKKPPTSSRPKNPMVSKQEKGLSSLGSPKDSQGTARESVFALDFLRQRLHEKIQLARGQGSTKELSAATLEKRQRRKQERERKKRKRKERQAKQQVAEAEKKEEPVEVTPKMACKELQESGLIFNKVEVTEEEPASKAQRKKEKRQKVKGNLTPLTGRNYRQLLDRLQARQGRLDELRDQDAAKAQELEAKMKWTNLLYKAEGVKIRDDERLLQEALKRKEKRRAQRQRKWEKRSEHVVEKMQQRQDKRRQNLRKKKAARAERRLQKAHKKGRVLPQDLERAGLS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
29PhosphorylationPGPERQRSTWGVRTK
CCCCHHHCCCCCCCC		21.8529514104
55PhosphorylationRKKTQKKSPEQEQKA
CCCCCCCCHHHHHHH		40.4823375375
93PhosphorylationSKQEKGLSSLGSPKD
CCCHHCHHHCCCCCC		31.9928833060
94PhosphorylationKQEKGLSSLGSPKDS
CCHHCHHHCCCCCCC		41.6228833060
97PhosphorylationKGLSSLGSPKDSQGT
HCHHHCCCCCCCCCC		33.7927087446
101PhosphorylationSLGSPKDSQGTARES
HCCCCCCCCCCHHHH		36.3124759943
104PhosphorylationSPKDSQGTARESVFA
CCCCCCCCHHHHHHH		18.2025777480
106CitrullinationKDSQGTARESVFALD
CCCCCCHHHHHHHHH		36.24-
106CitrullinationKDSQGTARESVFALD
CCCCCCHHHHHHHHH		36.2424463520
131PhosphorylationQLARGQGSTKELSAA
HHHCCCCCHHHHHHH		28.5529176673
132PhosphorylationLARGQGSTKELSAAT
HHCCCCCHHHHHHHH		35.0529176673
136PhosphorylationQGSTKELSAATLEKR
CCCHHHHHHHHHHHH		19.5629176673
179PhosphorylationKEEPVEVTPKMACKE
CCCCCCCCHHHHHHH		12.0428066266
190PhosphorylationACKELQESGLIFNKV
HHHHHHHHCCCEEEE		26.4128066266
200PhosphorylationIFNKVEVTEEEPASK
CEEEEECCCCCCCCH		24.9526060331
223PhosphorylationQKVKGNLTPLTGRNY
HHHCCCCCCCCCCCH		21.9122942356
226PhosphorylationKGNLTPLTGRNYRQL
CCCCCCCCCCCHHHH		34.9923984901
325AcetylationKRRQNLRKKKAARAE
HHHHHHHHHHHHHHH		62.896567105
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SURF6_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SURF6_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SURF6_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of SURF6_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SURF6_MOUSE

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Related Literatures of Post-Translational Modification

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