| UniProt ID | SURF1_HUMAN | |
|---|---|---|
| UniProt AC | Q15526 | |
| Protein Name | Surfeit locus protein 1 | |
| Gene Name | SURF1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 300 | |
| Subcellular Localization |
Mitochondrion inner membrane Multi-pass membrane protein. |
|
| Protein Description | Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly.. | |
| Protein Sequence | MAAVAALQLGLRAAGLGRAPASAAWRSVLRVSPRPGVAWRPSRCGSSAAEASATKAEDDSFLQWVLLLIPVTAFGLGTWQVQRRKWKLNLIAELESRVLAEPVPLPADPMELKNLEYRPVKVRGCFDHSKELYMMPRTMVDPVREAREGGLISSSTQSGAYVVTPFHCTDLGVTILVNRGFVPRKKVNPETRQKGQIEGEVDLIGMVRLTETRQPFVPENNPERNHWHYRDLEAMARITGAEPIFIDANFQSTVPGGPIGGQTRVTLRNEHLQYIVTWYGLSAATSYLWFKKFLRGTPGV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 52 | Phosphorylation | GSSAAEASATKAEDD CCCHHHHHCCCCCCC | 28.16 | - | |
| 110 | Sulfoxidation | VPLPADPMELKNLEY CCCCCCHHCCCCCCC | 10.96 | 21406390 | |
| 130 | Ubiquitination | RGCFDHSKELYMMPR EECCCCCCCEEECCC | 48.60 | - | |
| 210 | Phosphorylation | LIGMVRLTETRQPFV EEEEEEEECCCCCCC | 25.42 | 24043423 | |
| 212 | Phosphorylation | GMVRLTETRQPFVPE EEEEEECCCCCCCCC | 29.39 | 24043423 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SURF1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SURF1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SURF1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ACADV_HUMAN | ACADVL | physical | 26186194 | |
| ACADV_HUMAN | ACADVL | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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