| UniProt ID | STX5_MOUSE | |
|---|---|---|
| UniProt AC | Q8K1E0 | |
| Protein Name | Syntaxin-5 | |
| Gene Name | Stx5 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 355 | |
| Subcellular Localization |
Endoplasmic reticulum-Golgi intermediate compartment membrane Single-pass type IV membrane protein . Golgi apparatus membrane . Localizes throughout the Golgi apparatus, but most abundant in the cis-most cisternae. |
|
| Protein Description | Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus.. | |
| Protein Sequence | MIPRKRYGSKNTDQGVYLGLSKTQVLSPATAISSSSDSTPLPTPVALVPSPPDTMSCRDRTQEFQSACKSLQSRQNGIQTSKPALHAARQCSEFTLMARRIGKDLSNTFAKLEKLTILAKRKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVRAKGSQSGRHLQTHSNTIVVSLQSKLASMSNDFKSVLEVRTENLKQQRNRREQFSRAPVSALPLAPNNLGGGPIILGAESRASRDVAIDMMDPRTSQQLQLIDEQDSYIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEILKYFQSVTSNRWLMVKIFLILIVFFIIFVVFLA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 7 | Phosphorylation | -MIPRKRYGSKNTDQ -CCCCCCCCCCCCCC | 28.87 | 28833060 | |
| 9 | Phosphorylation | IPRKRYGSKNTDQGV CCCCCCCCCCCCCCE | 17.50 | 28833060 | |
| 12 | Phosphorylation | KRYGSKNTDQGVYLG CCCCCCCCCCCEEEC | 33.17 | 28833060 | |
| 17 | Phosphorylation | KNTDQGVYLGLSKTQ CCCCCCEEECCCCCE | 11.24 | 25159016 | |
| 69 | Ubiquitination | QEFQSACKSLQSRQN HHHHHHHHHHHHHHC | 54.65 | 22790023 | |
| 114 | Ubiquitination | NTFAKLEKLTILAKR HHHHHHHHHHHHHHC | 62.46 | 22790023 | |
| 120 | Ubiquitination | EKLTILAKRKSLFDD HHHHHHHHCHHCCCC | 57.84 | 22790023 | |
| 123 | Phosphorylation | TILAKRKSLFDDKAV HHHHHCHHCCCCCCE | 38.00 | 29514104 | |
| 137 | Phosphorylation | VEIEELTYIIKQDIN EEHHHHHHHHHHHHH | 17.17 | - | |
| 217 | Phosphorylation | QFSRAPVSALPLAPN HHHCCCCCCCCCCCC | 24.03 | 29514104 | |
| 252 | Phosphorylation | IDMMDPRTSQQLQLI ECCCCCCCHHHHHHH | 35.95 | 30635358 | |
| 253 | Phosphorylation | DMMDPRTSQQLQLID CCCCCCCHHHHHHHH | 19.74 | 30635358 | |
| 264 | Phosphorylation | QLIDEQDSYIQSRAD HHHHHHHHHHHHHHH | 24.67 | 29514104 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of STX5_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of STX5_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of STX5_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of STX5_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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