STR3N_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: STR3N_MOUSE
• UniProt AC: Q9DCI3
• Protein Name: STARD3 N-terminal-like protein {ECO:0000250|UniProtKB:O95772}
• Gene Name: Stard3nl {ECO:0000312|MGI:MGI:1923455}
• Organism: Mus musculus (Mouse).
• Sequence Length: 235
• Subcellular Localization: Late endosome membrane ; Multi-pass membrane protein . Localizes to contact sites between the endoplasmic reticulum and late endosomes: associates with the endoplasmic reticulum membrane via interaction with VAPA and VAPB.
• Protein Description: Tethering protein that creates contact site between the endoplasmic reticulum and late endosomes: localizes to late endosome membranes and contacts the endoplasmic reticulum via interaction with VAPA and VAPB..
• Protein Sequence: MNHLPEHMENTLTGSQSSHASLRDIHSINPAQLMARIESYEGREKKGISDVRRTFCLFVTFDLLFVTLLWIIELNVNGGIENTLKKEVIHYDYYSSYFDIFLLAVFRFKVLILGYAVCRLRHWWAIALTTAVTSAFLLAKVILSKLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEENRLLLVQDASERAALIPAGLSDGQFYSPPESEAGSEEEAEEKQESEKPLLEL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MNHLPEHM -------CCCCHHHH		-
11	Phosphorylation	LPEHMENTLTGSQSS CHHHHHHCCCCCCCC		26643407
13	Phosphorylation	EHMENTLTGSQSSHA HHHHHCCCCCCCCCC		26643407
15	Phosphorylation	MENTLTGSQSSHASL HHHCCCCCCCCCCCH		26643407
17	Phosphorylation	NTLTGSQSSHASLRD HCCCCCCCCCCCHHH		26643407
18	Phosphorylation	TLTGSQSSHASLRDI CCCCCCCCCCCHHHH		26643407
21	Phosphorylation	GSQSSHASLRDIHSI CCCCCCCCHHHHHHC		26643407
27	Phosphorylation	ASLRDIHSINPAQLM CCHHHHHHCCHHHHH		19144319
39	Phosphorylation	QLMARIESYEGREKK HHHHHHHHHCCCHHC		26824392
40	Phosphorylation	LMARIESYEGREKKG HHHHHHHHCCCHHCC		28066266
193	Phosphorylation	LLLVQDASERAALIP EEEEECHHHHHHHCC		27087446
204	Phosphorylation	ALIPAGLSDGQFYSP HHCCCCCCCCCCCCC		21743459
209	Phosphorylation	GLSDGQFYSPPESEA CCCCCCCCCCCCCCC		21743459
210	Phosphorylation	LSDGQFYSPPESEAG CCCCCCCCCCCCCCC		27087446
214	Phosphorylation	QFYSPPESEAGSEEE CCCCCCCCCCCCHHH		27087446
218	Phosphorylation	PPESEAGSEEEAEEK CCCCCCCCHHHHHHH		27087446
228	Phosphorylation	EAEEKQESEKPLLEL HHHHHHHHCCCCCCC		21743459

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of STR3N_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of STR3N_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of STR3N_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of STR3N_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.