STOX2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: STOX2_HUMAN
• UniProt AC: Q9P2F5
• Protein Name: Storkhead-box protein 2
• Gene Name: STOX2
• Organism: Homo sapiens (Human).
• Sequence Length: 926
• Protein Sequence: MKKTRSTTLRRAWPSSDFSDRASDRMRSRSEKDYRLHKRFPAAFAPQASRGYMTSGDVSPISMSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFPGVPTPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQTYFITPSLIRTNSKWYHLDERIPDRSQCTSPQPGTITPSASGCVRERTLPRNHCDSCHCCREDVHSTHAPTLQRKSAKDCKDPYCPPSLCQVPPTEKSKSTVNFSYKTETLSKPKDSEKQSKKFGLKLFRLSFKKDKTKQLANFSAQFPPEEWPLRDEDTPATIPREVEMEIIRRINPDLTVENVMRHTALMKKLEEEKAQRSKAGSSAHHSGRSKKSRTHRKSHGKSRSHSKTRVSKGDPSDGSHLDIPAEREYDFCDPLTRVPREGCFIIEHKGDNFIMHSNTNVLESHFPMTPEWDVSGELAKRRTEMPFPEPSRGSSHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEGCSQDDQTPSQSYIDDSTLRPAQTVSLQRAHISSTSYKEVCIPEIVSGSKEPSSACSLLEPGKPPESLPSYGELNSCPTKTATDDYFQCNTSSETVLTAPSPLGKNKEDHDTLTLAEGVKKLSPSDRQVPHSSREPVGHKEESPKGPGGGPAASGGVAEGIANGRLVQHHGAEPSSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEPSLGTSAAQAMPASQRQQESGGNQEASFDYYNVSDDDDSEEGANKNTEEEKNREDVGTMQWLLEREKERDLQRKFEKNLTLLAPKETDSSSNQRATHSARLDSMDSSSITVDSGFNSPRTRESLASNTSSIVESNRRQNPALSPAHGGAGPAFNFRASAEPPTNEAEKLQKPSNCLQASVTSV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MKKTRSTTLRRAWP -CCCCCCCCHHHHCC	26.93	-
8	Phosphorylation	MKKTRSTTLRRAWPS CCCCCCCCHHHHCCC	21.36	-
130	Phosphorylation	LVRERKIYPTPDGYF HHHHCCCCCCCCCEE	12.23	-
155	Phosphorylation	PSLIRTNSKWYHLDE HHHHCCCCCCEECCC	24.77	28857561
168	Phosphorylation	DERIPDRSQCTSPQP CCCCCCHHHCCCCCC	36.67	22210691
171	Phosphorylation	IPDRSQCTSPQPGTI CCCHHHCCCCCCCCC	35.49	25159151
172	Phosphorylation	PDRSQCTSPQPGTIT CCHHHCCCCCCCCCC	29.21	25159151
179	Phosphorylation	SPQPGTITPSASGCV CCCCCCCCCCCCCCC	15.84	28555341
213	Phosphorylation	VHSTHAPTLQRKSAK HHCCCCHHHCCCCCC	35.98	33259812
237	Phosphorylation	SLCQVPPTEKSKSTV HHCCCCCCCCCCCEE	50.39	-
248	Phosphorylation	KSTVNFSYKTETLSK CCEEEEEEEECCCCC	20.14	-
254	Phosphorylation	SYKTETLSKPKDSEK EEEECCCCCCCCCHH	55.09	24719451
274	Phosphorylation	GLKLFRLSFKKDKTK CHHHHHHEECCCCHH	30.66	24719451
384	Phosphorylation	RVSKGDPSDGSHLDI CCCCCCCCCCCCCCC	60.38	29255136
387	Phosphorylation	KGDPSDGSHLDIPAE CCCCCCCCCCCCCCC	26.35	29255136
397	Phosphorylation	DIPAEREYDFCDPLT CCCCCCCCCCCCCCC	22.12	28674419
404	Phosphorylation	YDFCDPLTRVPREGC CCCCCCCCCCCCCCE	34.70	-
448	Ubiquitination	DVSGELAKRRTEMPF CCCHHHHHHCCCCCC	55.85	-
459	Phosphorylation	EMPFPEPSRGSSHSK CCCCCCCCCCCCCCH	47.84	28387310
460	Methylation	MPFPEPSRGSSHSKV CCCCCCCCCCCCCHH	60.78	115917969
491	Phosphorylation	SNKAKERSRSMDNSK HHHHHHHHHHCCCCC	29.78	28985074
517	Phosphorylation	EDLAEGCSQDDQTPS HHHHCCCCCCCCCCC	47.72	-
550	Phosphorylation	RAHISSTSYKEVCIP EEECCCCCCHHEECH	35.83	28985074
551	Phosphorylation	AHISSTSYKEVCIPE EECCCCCCHHEECHH	15.97	28985074
563	Phosphorylation	IPEIVSGSKEPSSAC CHHHCCCCCCCCCCC	26.75	28985074
567	Phosphorylation	VSGSKEPSSACSLLE CCCCCCCCCCCHHCC	31.49	22210691
590	Phosphorylation	PSYGELNSCPTKTAT CCCCCCCCCCCCCCC	33.81	22210691
593	Phosphorylation	GELNSCPTKTATDDY CCCCCCCCCCCCCCC	45.41	22210691
628	Phosphorylation	KEDHDTLTLAEGVKK CCCCCHHHHHHHHHH	26.47	-
637	Phosphorylation	AEGVKKLSPSDRQVP HHHHHHCCCCCCCCC	31.10	23532336
639	Phosphorylation	GVKKLSPSDRQVPHS HHHHCCCCCCCCCCC	41.89	23532336
647	Phosphorylation	DRQVPHSSREPVGHK CCCCCCCCCCCCCCC	37.31	15302935
657	Phosphorylation	PVGHKEESPKGPGGG CCCCCCCCCCCCCCC	32.76	28985074
690	Phosphorylation	HHGAEPSSLDKRKEI CCCCCCCHHHHHHHH	51.83	28555341
699	Phosphorylation	DKRKEIFSKDTLFKP HHHHHHCCCCCCCHH	34.97	24719451
722	Phosphorylation	SYHKSSLSLLKSHPK CCCHHHHHHHHHCCC	33.34	24719451
734	Phosphorylation	HPKTPADTLPGRCEK CCCCCCCCCCCCCCC	36.64	28985074
839	Phosphorylation	SSSNQRATHSARLDS CCCCCCCCCHHCCCC	20.67	22210691
846	Phosphorylation	THSARLDSMDSSSIT CCHHCCCCCCCCCCE	29.13	22210691
856	Phosphorylation	SSSITVDSGFNSPRT CCCCEECCCCCCCHH	40.73	22210691
860	Phosphorylation	TVDSGFNSPRTRESL EECCCCCCCHHHHHH	17.31	28674419
866	Phosphorylation	NSPRTRESLASNTSS CCCHHHHHHHHCHHH	26.41	29083192
869	Phosphorylation	RTRESLASNTSSIVE HHHHHHHHCHHHHHH	46.03	29083192
871	Phosphorylation	RESLASNTSSIVESN HHHHHHCHHHHHHHC	22.74	29083192
872	Phosphorylation	ESLASNTSSIVESNR HHHHHCHHHHHHHCC	23.48	29083192
873	Phosphorylation	SLASNTSSIVESNRR HHHHCHHHHHHHCCC	28.72	24275569
877	Phosphorylation	NTSSIVESNRRQNPA CHHHHHHHCCCCCCC	25.41	29083192
886	Phosphorylation	RRQNPALSPAHGGAG CCCCCCCCCCCCCCC	23.34	23312004
901	Phosphorylation	PAFNFRASAEPPTNE CCCCCCCCCCCCCCH	28.98	-
906	Phosphorylation	RASAEPPTNEAEKLQ CCCCCCCCCHHHHHC	57.30	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of STOX2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of STOX2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of STOX2_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of STOX2_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.