STNA_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: STNA_DROME
• UniProt AC: Q24211
• Protein Name: Protein stoned-A
• Gene Name: stnA
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 850
• Subcellular Localization: Cytoplasm. Cell junction, synapse. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Colocalizes with synaptic vesicle pools. Colocalizes with the endocytic network within synaptic boutons.
• Protein Description: Adapter protein involved in endocytic recycling of synaptic vesicles membranes. May act by mediating the retrieval of synaptotagmin protein Syt from the plasma membrane, thereby facilitating the internalization of multiple synaptic vesicles from the plasma membrane..
• Protein Sequence: MLKLPKGLKKKKKKSKKDQELFTEEELEQYKRDLKAKQEAAATKSDAGESDGASSDVEAHHEPVAFNSGLGSGSSSSILNAQQQLSDQNQGAAGGDEEWAKFKALTSGVDSILHKTQDELDRIKKESFYQRLPSAAEKKKQKEEEAARLEAEQQEREKQRLGQIEAQRDKLAEAVVQLSESEEEAGDYEADDIFATDYIEAITSGELQLAVVPDSPVLAEDGPDPFDTAYAEKVIVGADRAKGNKKLVSLGAAVEVLSGRVDREHAVALANPKRKLRKGIQNLLLSESIELADSEAELLAATSNAEPQHNLLDDLDEELSESSVPIDLSVSLHLHLIKHKQPVEEEEELEQKGRENQLLNPDLSEFDSLKDEEDDEFAELAAESLTKKEEVTVVSQVVLPVAQLPTEAFEAGSWAEFEEQSGQEPGKPKRPPPPVRPPTGPHIVPGAIYVSEDEEENPEDDPFNTNYAEQVIKKTTVLEEDDDFDPRAEEHATEPPFLAAPQRDLLAGSATDLSQVVPAPLAPTLSVDQEAEDFDPFDTSAVSALVQPKSTELRFLERELLNYSGLDGVTLKHSLSDQDFDPRADQKEPAAPQVKLEQKETDFDTAQRKSSLSLNIQAKSVGFLVPASDLLGAGNELGASKKPLTPYYAPSDNRLQEREREAEDVDPFDTSHVPEAKLSDIELKHIEKDLISVPANLRHSLSDPDFDPRAPPTPVPAEVLLAVEENINIKVLTPAQDRKKLTNSGGSGKSEEDIDPFDTSIAANLQPGQTELKLLENELLPETKTLVTDVLDVQSDAQELGLGDKVLTPSTHSRPSLPAQDIDPFDTSIAENLAPGEAEIKLLESELIER

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
368	Phosphorylation	PDLSEFDSLKDEEDD CCHHHHHCCCCCCCH	42.51	27794539
610	Phosphorylation	FDTAQRKSSLSLNIQ CCHHHHHHHCCCEEE	38.41	27794539
611	Phosphorylation	DTAQRKSSLSLNIQA CHHHHHHHCCCEEEE	25.64	27794539
742	Phosphorylation	AQDRKKLTNSGGSGK HHHHHHHCCCCCCCC	35.90	27794539
744	Phosphorylation	DRKKLTNSGGSGKSE HHHHHCCCCCCCCCH	39.02	27794539
747	Phosphorylation	KLTNSGGSGKSEEDI HHCCCCCCCCCHHHC	46.72	27794539
750	Phosphorylation	NSGGSGKSEEDIDPF CCCCCCCCHHHCCCC	50.14	27794539
816	Phosphorylation	PSTHSRPSLPAQDID CCCCCCCCCCHHHCC	45.97	27794539

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of STNA_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of STNA_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of STNA_DROME !!

Protein-Protein Interaction

Oops, there are no PPI records of STNA_DROME !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.