STM_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: STM_ARATH
• UniProt AC: Q38874
• Protein Name: Homeobox protein SHOOT MERISTEMLESS {ECO:0000303|PubMed:8538741}
• Gene Name: STM {ECO:0000303|PubMed:8538741}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 382
• Subcellular Localization: Nucleus . Cell junction, plasmodesma . Cytoplasm . Association with TALE/BELL proteins is necessary for nuclear location (PubMed:16513846). Dynamic localization via a plasmodesmata-mediated cell-to-cell transport. This shuttle is repressed by MBP2C b
• Protein Description: Required for shoot apical meristem (SAM) formation during embryogenesis. Negatively regulates ASYMMETRIC LEAVES1 (AS1) and ASYMMETRIC LEAVES2 (AS2 or LBD6). Probably binds to the DNA sequence 5'-TGAC-3'. Binds to RNA (By similarity)..
• Protein Sequence: MESGSNSTSCPMAFAGDNSDGPMCPMMMMMPPIMTSHQHHGHDHQHQQQEHDGYAYQSHHQQSSSLFLQSLAPPQGTKNKVASSSSPSSCAPAYSLMEIHHNEIVAGGINPCSSSSSSASVKAKIMAHPHYHRLLAAYVNCQKVGAPPEVVARLEEACSSAAAAAASMGPTGCLGEDPGLDQFMEAYCEMLVKYEQELSKPFKEAMVFLQRVECQFKSLSLSSPSSFSGYGETAIDRNNNGSSEEEVDMNNEFVDPQAEDRELKGQLLRKYSGYLGSLKQEFMKKRKKGKLPKEARQQLLDWWSRHYKWPYPSEQQKLALAESTGLDQKQINNWFINQRKRHWKPSEDMQFVVMDATHPHHYFMDNVLGNPFPMDHISSTML

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
271	Phosphorylation	KGQLLRKYSGYLGSL HHHHHHHHHHHHHHH	10.82	25561503
272	Phosphorylation	GQLLRKYSGYLGSLK HHHHHHHHHHHHHHH	24.81	25561503
274	Phosphorylation	LLRKYSGYLGSLKQE HHHHHHHHHHHHHHH	11.27	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of STM_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of STM_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of STM_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BEL1_ARATH	BEL1	physical	11701881
BLH9_ARATH	RPL	physical	16513846
BLH3_ARATH	BLH3	physical	16513846
ATH1_ARATH	ATH1	physical	16513846

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.