STKL1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: STKL1_HUMAN
• UniProt AC: Q8NE28
• Protein Name: Serine/threonine kinase-like domain-containing protein STKLD1
• Gene Name: STKLD1
• Organism: Homo sapiens (Human).
• Sequence Length: 680
• Protein Sequence: MLGPGSNRRRPTQGERGPGSPGEPMEKYQVLYQLNPGALGVNLVVEEMETKVKHVIKQVECMDDHYASQALEELMPLLKLRHAHISVYQELFITWNGEISSLYLCLVMEFNELSFQEVIEDKRKAKKIIDSEWMQNVLGQVLDALEYLHHLDIIHRNLKPSNIILISSDHCKLQDLSSNVLMTDKAKWNIRAEEDPFRKSWMAPEALNFSFSQKSDIWSLGCIILDMTSCSFMDGTEAMHLRKSLRQSPGSLKAVLKTMEEKQIPDVETFRNLLPLMLQIDPSDRITIKDVVHITFLRGSFKSSCVSLTLHRQMVPASITDMLLEGNVASILEVMQKFSGWPEVQLRAMKRLLKMPADQLGLPWPPELVEVVVTTMELHDRVLDVQLCACSLLLHLLGQALVHHPEAKAPCNQAITSTLLSALQSHPEEEPLLVMVYSLLAITTTQESESLSEELQNAGLLEHILEHLNSSLESRDVCASGLGLLWALLLDGIIVNKAPLEKVPDLISQVLATYPADGEMAEASCGVFWLLSLLGCIKEQQFEQVVALLLQSIRLCQDRALLVNNAYRGLASLVKVSELAAFKVVVQEEGGSGLSLIKETYQLHRDDPEVVENVGMLLVHLASYEEILPELVSSSMKALLQEIKERFTSSLVSDSSAFSKPGLPPGGSPQLGCTTSGGLE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
177	Phosphorylation	HCKLQDLSSNVLMTD CCCCCCCCCCCCCCC		-
178	Phosphorylation	CKLQDLSSNVLMTDK CCCCCCCCCCCCCCH		-
183	Phosphorylation	LSSNVLMTDKAKWNI CCCCCCCCCHHHCCC		-
283	Phosphorylation	LMLQIDPSDRITIKD HHHCCCCCCCEEHHE		27542207
287	Phosphorylation	IDPSDRITIKDVVHI CCCCCCEEHHEEEEE		27542207
295	Phosphorylation	IKDVVHITFLRGSFK HHEEEEEEEECCCCH		20058876
337	Acetylation	SILEVMQKFSGWPEV HHHHHHHHHCCCHHH		7692195
572	Phosphorylation	NAYRGLASLVKVSEL CHHHHHHHHHHHHHH		24719451
592	Phosphorylation	VVQEEGGSGLSLIKE EEEECCCCCHHHHHH		27251275
595	Phosphorylation	EEGGSGLSLIKETYQ ECCCCCHHHHHHHHH		24719451
600	Phosphorylation	GLSLIKETYQLHRDD CHHHHHHHHHHCCCC		27251275
624	Phosphorylation	LLVHLASYEEILPEL HHHHHHCHHHHHHHH		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of STKL1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of STKL1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of STKL1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of STKL1_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.