STK31_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: STK31_HUMAN
• UniProt AC: Q9BXU1
• Protein Name: Serine/threonine-protein kinase 31
• Gene Name: STK31
• Organism: Homo sapiens (Human).
• Sequence Length: 1019
• Protein Sequence: MWVQGHSSRASATESVSFSGIVQMDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMKIGCSLSEVCPQASSVLGNLDPNKIYGGLFSEDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDIVEIPLELQFSSVAKKYKLWGLHIPSDQEVTQFDQGTTFLGSLIFEKEIKMRIKATSEDGTVIAQAEYGSVDIGEEVLKKGFAEKCRLASRTDICEEKKLDPGQLVLRNLKSPIPLWGHRSNQSTFSRPKGHLSEKMTLDLKDENDAGNLITFPKESLAVGDFNLGSNVSLEKIKQDQKLIEENEKLKTEKDALLESYKALELKVEQIAQELQQEKAAAVDLTNHLEYTLKTYIDTRMKNLAAKMEILKEMRHVDISVRFGKDLSDAIQVLDEGCFTTPASLNGLEIIWAEYSLAQENIKTCEYVSEGNILIAQRNEMQQKLYMSVEDFILEVDESSLNKRLKTLQDLSVSLEAVYGQAKEGANSDEILKKFYDWKCDKREEFTSVRSETDASLHRLVAWFQRTLKVFDLSVEGSLISEDAMDNIDEILEKTESSVCKELEIALVDQGDADKEIISNTYSQVLQKIHSEERLIATVQAKYKDSIEFKKQLIEYLNKSPSVDHLLSIKKTLKSLKALLRWKLVEKSNLEESDDPDGSQIEKIKEEITQLRNNVFQEIYHEREEYEMLTSLAQKWFPELPLLHPEIGLLKYMNSGGLLTMSLERDLLDAEPMKELSSKRPLVRSEVNGQIILLKGYSVDVDTEAKVIERAATYHRAWREAEGDSGLLPLIFLFLCKSDPMAYLMVPYYPRANLNAVQANMPLNSEETLKVMKGVAQGLHTLHKADIIHGSLHQNNVFALNREQGIVGDFDFTKSVSQRASVNMMVGDLSLMSPELKMGKPASPGSDLYAYGCLLLWLSVQNQEFEINKDGIPKVDQFHLDDKVKSLLCSLICYRSSMTAEQVLNAECFLMPKEQSVPNPEKDTEYTLYKKEEEIKTENLDKCMEKTRNGEANFDC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
28	Phosphorylation	IVQMDEDTHYDKVED EEECCCCCCCCCHHH	21.93	-
30	Phosphorylation	QMDEDTHYDKVEDVV ECCCCCCCCCHHHHH	21.39	-
119	Phosphorylation	RYIDYGNTEILNRSD EEECCCCCEEECHHH	21.75	27732954
125	Phosphorylation	NTEILNRSDIVEIPL CCEEECHHHCEEECC	30.53	-
137	Phosphorylation	IPLELQFSSVAKKYK ECCEEECHHHHHHHC	15.79	-
138	Phosphorylation	PLELQFSSVAKKYKL CCEEECHHHHHHHCE	27.64	-
152	Phosphorylation	LWGLHIPSDQEVTQF EEEEECCCCCCEEEC	51.85	-
163	Phosphorylation	VTQFDQGTTFLGSLI EEECCCCCCEEHHHH	14.56	-
182	Phosphorylation	IKMRIKATSEDGTVI EEEEEEEECCCCCEE	27.87	-
187	Phosphorylation	KATSEDGTVIAQAEY EEECCCCCEEEEEEE	22.51	-
278	Phosphorylation	NDAGNLITFPKESLA CCCCCEEEECHHHEE	36.73	-
293	Phosphorylation	VGDFNLGSNVSLEKI CCCCCCCCCCCHHHH	36.91	22210691
375	Acetylation	AAKMEILKEMRHVDI HHHHHHHHHHCCCCC	55.94	11792161
427	Phosphorylation	LAQENIKTCEYVSEG HHHCCCCCCEEEECC	13.53	28509920
430	Phosphorylation	ENIKTCEYVSEGNIL CCCCCCEEEECCCEE	16.06	28509920
432	Phosphorylation	IKTCEYVSEGNILIA CCCCEEEECCCEEEE	38.59	28509920
449	Phosphorylation	NEMQQKLYMSVEDFI HHHHHHHHCCHHHHH	8.38	-
451	Phosphorylation	MQQKLYMSVEDFILE HHHHHHCCHHHHHHH	14.59	-
470	Phosphorylation	SLNKRLKTLQDLSVS HHHHHHHHHHHHHHH	33.95	23663014
475	Phosphorylation	LKTLQDLSVSLEAVY HHHHHHHHHHHHHHH	20.25	23663014
477	Phosphorylation	TLQDLSVSLEAVYGQ HHHHHHHHHHHHHHH	19.67	23663014
482	Phosphorylation	SVSLEAVYGQAKEGA HHHHHHHHHHHHCCC	15.57	23663014
606	Phosphorylation	IATVQAKYKDSIEFK HHHHHHHHCCCHHHH	24.04	28509920
619	Phosphorylation	FKKQLIEYLNKSPSV HHHHHHHHHHCCCCH	14.47	23532336
631	Phosphorylation	PSVDHLLSIKKTLKS CCHHHHHHHHHHHHH	38.43	24719451
718	O-linked_Glycosylation	GLLKYMNSGGLLTMS CHHHHHHCCCEEEEE	20.08	30379171
723	O-linked_Glycosylation	MNSGGLLTMSLERDL HHCCCEEEEEHHHHC	15.12	30379171
740	Phosphorylation	AEPMKELSSKRPLVR CHHHHHHCCCCCCEE	34.60	23401153
741	Phosphorylation	EPMKELSSKRPLVRS HHHHHHCCCCCCEEE	45.36	23401153
748	Phosphorylation	SKRPLVRSEVNGQII CCCCCEEEEECCEEE	38.12	22210691
760	Phosphorylation	QIILLKGYSVDVDTE EEEEEECEEEECCCH	12.16	22210691
761	Phosphorylation	IILLKGYSVDVDTEA EEEEECEEEECCCHH	22.10	22210691
766	Phosphorylation	GYSVDVDTEAKVIER CEEEECCCHHHHHHH	37.38	-
777	Phosphorylation	VIERAATYHRAWREA HHHHHHHHHHHHHHH	5.65	25884760
884	Phosphorylation	KSVSQRASVNMMVGD CCHHHHHHHEEEECC	19.06	-
893	Phosphorylation	NMMVGDLSLMSPELK EEEECCHHHCCCHHC	27.11	23532336
896	Phosphorylation	VGDLSLMSPELKMGK ECCHHHCCCHHCCCC	22.10	24719451
992	Phosphorylation	KDTEYTLYKKEEEIK CCCCEEEEECHHHHC	16.53	22817900
1010	Phosphorylation	LDKCMEKTRNGEANF HHHHHHHHCCCCCCC	18.96	26307563

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of STK31_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of STK31_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of STK31_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of STK31_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.