dbPTM

ST32A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ST32A_HUMAN
UniProt AC	Q8WU08
Protein Name	Serine/threonine-protein kinase 32A
Gene Name	STK32A
Organism	Homo sapiens (Human).
Sequence Length	396
Subcellular Localization	Cell membrane Lipid-anchor .
Protein Description
Protein Sequence	MGANTSRKPPVFDENEDVNFDHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFKEETVKLFICELVMALDYLQNQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPRETQITTMAGTKPYMAPEMFSSRKGAGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVHTFETTVVTYPSAWSQEMVSLLKKLLEPNPDQRFSQLSDVQNFPYMNDINWDAVFQKRLIPGFIPNKGRLNCDPTFELEEMILESKPLHKKKKRLAKKEKDMRKCDSSQTCLLQEHLDSVQKEFIIFNREKVNRDFNKRQPNLALEQTKDPQGEDGQNNNL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Myristoylation	------MGANTSRKP ------CCCCCCCCC	27.77	25043870
49	Phosphorylation	KNDTKKMYAMKYMNK CCCCHHHHHHHHHCH	16.66	21712546
175	Phosphorylation	AAMLPRETQITTMAG EEECCCCCEEECCCC	26.93	-
194	Phosphorylation	MAPEMFSSRKGAGYS ECHHHHHCCCCCCCE	27.09	-
255	Phosphorylation	AWSQEMVSLLKKLLE CCCHHHHHHHHHHHC	27.03	24719451
320	Phosphorylation	LEEMILESKPLHKKK HHHHHHHCCCCHHHH	35.81	24719451
342 (in isoform 3)	Phosphorylation	-	33.54	22210691
343 (in isoform 3)	Phosphorylation	-	19.09	22210691
357 (in isoform 3)	Phosphorylation	-	53.06	22210691

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ST32A_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ST32A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ST32A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
CYTF_HUMAN	CST7	physical	28514442

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ST32A_HUMAN

Related Literatures of Post-Translational Modification