dbPTM

SRRM1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SRRM1_MOUSE
UniProt AC	Q52KI8
Protein Name	Serine/arginine repetitive matrix protein 1
Gene Name	Srrm1
Organism	Mus musculus (Mouse).
Sequence Length	946
Subcellular Localization	Nucleus matrix . Nucleus speckle .
Protein Description	Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates (By similarity)..
Protein Sequence	MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASLKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKSPELPEPSVRMKDSSVQEATSTSDILKAPKPEPVPEPKEPSPEKNSKKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPGRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSSPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGSKMAAADSVQQRRQYRRQNQQSSSDSGSSSTSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRMQMGKRWQSPVTKSSRRRRSPSPPPARRRRSPSPAPPPPPPPPPPRRRRSPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNKRHSPSPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKTAMATQRNIRRVSKSPKADSLSRAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPARNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVTIATPATAAPAAVSAATTTSAQEEPAAAPEPRKETESEAEDDNLDDLERHLREKALRSMRKAQVSPQS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MDAGFFRG -------CCCCCCCC	7.81	-
7	Citrullination	-MDAGFFRGTSAEQD -CCCCCCCCCCHHHC	45.26	-
7	Citrullination	-MDAGFFRGTSAEQD -CCCCCCCCCCHHHC	45.26	24463520
9	Phosphorylation	DAGFFRGTSAEQDNR CCCCCCCCCHHHCCC	22.10	26745281
10	Phosphorylation	AGFFRGTSAEQDNRF CCCCCCCCHHHCCCC	32.41	26824392
18	Phosphorylation	AEQDNRFSNKQKKLL HHHCCCCCHHHHHHH	39.62	30635358
29	Acetylation	KKLLKQLKFAECLEK HHHHHHHHHHHHHHH	39.78	23806337
36	Malonylation	KFAECLEKKVDMSKV HHHHHHHHHCCHHHC	45.19	26320211
140	Acetylation	QRQIEQEKLASLKKQ HHHHHHHHHHHHHHH	49.39	23806337
169	Phosphorylation	SREKRERSRSPRRRK HHHHHHHHHCHHHHH	32.15	27717184
171	Phosphorylation	EKRERSRSPRRRKSR HHHHHHHCHHHHHCC	24.81	23384938
177	Phosphorylation	RSPRRRKSRSPSPRR HCHHHHHCCCCCCCC	35.86	29895711
179	Phosphorylation	PRRRKSRSPSPRRRS HHHHHCCCCCCCCCC	36.50	29895711
181	Phosphorylation	RRKSRSPSPRRRSSP HHHCCCCCCCCCCCH	32.08	23737553
186	Phosphorylation	SPSPRRRSSPVRRER CCCCCCCCCHHHHHH	36.86	23140645
187	Phosphorylation	PSPRRRSSPVRRERK CCCCCCCCHHHHHHH	26.13	26824392
196	Phosphorylation	VRRERKRSHSRSPRH HHHHHHHHHCCCCCC	28.93	-
198	Phosphorylation	RERKRSHSRSPRHRT HHHHHHHCCCCCCCC	35.38	-
200	Phosphorylation	RKRSHSRSPRHRTKS HHHHHCCCCCCCCCC	29.33	-
205	Phosphorylation	SRSPRHRTKSRSPSP CCCCCCCCCCCCCCC	27.52	25159016
207	Phosphorylation	SPRHRTKSRSPSPAP CCCCCCCCCCCCCCC	37.06	27087446
209	Phosphorylation	RHRTKSRSPSPAPEK CCCCCCCCCCCCCCC	36.50	27087446
211	Phosphorylation	RTKSRSPSPAPEKKE CCCCCCCCCCCCCCC	34.63	27087446
220	Phosphorylation	APEKKEKSPELPEPS CCCCCCCCCCCCCCC	25.38	27087446
227	Phosphorylation	SPELPEPSVRMKDSS CCCCCCCCCCCCCCC	22.24	24925903
233	Phosphorylation	PSVRMKDSSVQEATS CCCCCCCCCHHCCCC	27.22	28833060
234	Phosphorylation	SVRMKDSSVQEATST CCCCCCCCHHCCCCH	37.64	28833060
239	Phosphorylation	DSSVQEATSTSDILK CCCHHCCCCHHHHHH	31.61	28833060
240	Phosphorylation	SSVQEATSTSDILKA CCHHCCCCHHHHHHC	32.72	28833060
241	Phosphorylation	SVQEATSTSDILKAP CHHCCCCHHHHHHCC	26.51	28833060
242	Phosphorylation	VQEATSTSDILKAPK HHCCCCHHHHHHCCC	23.56	28833060
260	Phosphorylation	VPEPKEPSPEKNSKK CCCCCCCCCCCCCHH	46.94	24925903
265	Phosphorylation	EPSPEKNSKKEKEKT CCCCCCCCHHHHHHC	57.06	25619855
288	Phosphorylation	KSRSRTRSRSPSHTR HHHCCCCCCCCCCCC	36.18	25159016
290	Phosphorylation	RSRTRSRSPSHTRPR HCCCCCCCCCCCCCC	31.81	25159016
292	Phosphorylation	RTRSRSPSHTRPRRR CCCCCCCCCCCCCHH	38.44	25159016
294	Phosphorylation	RSRSPSHTRPRRRHR CCCCCCCCCCCHHHH	46.86	25159016
302	Phosphorylation	RPRRRHRSRSRSYSP CCCHHHHHCCCCCCC	28.60	22324799
304	Phosphorylation	RRRHRSRSRSYSPRR CHHHHHCCCCCCCCC	27.16	23684622
306	Phosphorylation	RHRSRSRSYSPRRRP HHHHCCCCCCCCCCC	31.07	23684622
307	Phosphorylation	HRSRSRSYSPRRRPS HHHCCCCCCCCCCCC	22.91	22802335
308	Phosphorylation	RSRSRSYSPRRRPSP HHCCCCCCCCCCCCC	17.12	23684622
314	Phosphorylation	YSPRRRPSPRRRPSP CCCCCCCCCCCCCCC	29.27	23737553
320	Phosphorylation	PSPRRRPSPRRRTPP CCCCCCCCCCCCCCC	29.27	23737553
325	Phosphorylation	RPSPRRRTPPRRMPP CCCCCCCCCCCCCCC	35.51	23384938
339	Phosphorylation	PPPRHRRSRSPGRRR CCCCCCCCCCCCCCC	36.75	23737553
341	Phosphorylation	PRHRRSRSPGRRRRR CCCCCCCCCCCCCCC	32.71	23737553
354	Phosphorylation	RRSSASLSGSSSSSS CCCCCCCCCCCCCCC	33.85	21183079
361	Phosphorylation	SGSSSSSSSSRSRSP CCCCCCCCCCCCCCC	33.99	21183079
362	Phosphorylation	GSSSSSSSSRSRSPP CCCCCCCCCCCCCCC	31.55	21183079
363	Phosphorylation	SSSSSSSSRSRSPPK CCCCCCCCCCCCCCC	35.90	25890499
367	Phosphorylation	SSSSRSRSPPKKPPK CCCCCCCCCCCCCCC	46.96	28066266
376	Phosphorylation	PKKPPKRTSSPPRKT CCCCCCCCCCCCCCC	39.42	26745281
377	Phosphorylation	KKPPKRTSSPPRKTR CCCCCCCCCCCCCCC	44.90	24899341
378	Phosphorylation	KPPKRTSSPPRKTRR CCCCCCCCCCCCCCC	38.01	23375375
383	Phosphorylation	TSSPPRKTRRLSPSA CCCCCCCCCCCCCCC	23.46	26643407
387	Phosphorylation	PRKTRRLSPSASPPR CCCCCCCCCCCCCCC	18.26	18388127
389	Phosphorylation	KTRRLSPSASPPRRR CCCCCCCCCCCCCCC	37.69	27087446
391	Phosphorylation	RRLSPSASPPRRRHR CCCCCCCCCCCCCCC	39.51	18388127
400	Phosphorylation	PRRRHRPSSPATPPP CCCCCCCCCCCCCCC	49.24	21930439
401	Phosphorylation	RRRHRPSSPATPPPK CCCCCCCCCCCCCCC	22.64	18388127
404	Phosphorylation	HRPSSPATPPPKTRH CCCCCCCCCCCCCCC	39.45	18388127
409	Phosphorylation	PATPPPKTRHSPTPQ CCCCCCCCCCCCCCC	39.11	25521595
412	Phosphorylation	PPPKTRHSPTPQQSN CCCCCCCCCCCCCCC	27.46	25521595
414	Phosphorylation	PKTRHSPTPQQSNRT CCCCCCCCCCCCCCC	36.42	25521595
418	Phosphorylation	HSPTPQQSNRTRKSR CCCCCCCCCCCCCCC	24.03	27087446
424	Phosphorylation	QSNRTRKSRVSVSPG CCCCCCCCCEEECCC	34.32	27087446
427	Phosphorylation	RTRKSRVSVSPGRTS CCCCCCEEECCCCCC	18.77	27087446
429	Phosphorylation	RKSRVSVSPGRTSGK CCCCEEECCCCCCCC	17.71	27087446
433	Phosphorylation	VSVSPGRTSGKVTKH EEECCCCCCCCEEEC	47.98	25521595
434	Phosphorylation	SVSPGRTSGKVTKHK EECCCCCCCCEEECC	34.94	23375375
443	Phosphorylation	KVTKHKGTEKRESPS CEEECCCCCCCCCCC	43.04	25159016
448	Phosphorylation	KGTEKRESPSPAPKP CCCCCCCCCCCCCCC	34.41	26824392
450	Phosphorylation	TEKRESPSPAPKPRK CCCCCCCCCCCCCCE	42.86	21930439
461	Phosphorylation	KPRKVELSESEEDKG CCCEECCCCCCCCHH	26.10	27087446
463	Phosphorylation	RKVELSESEEDKGSK CEECCCCCCCCHHCH	42.80	27087446
469	Phosphorylation	ESEEDKGSKMAAADS CCCCCHHCHHHHHHH	25.62	21082442
470	Ubiquitination	SEEDKGSKMAAADSV CCCCHHCHHHHHHHH	41.02	22790023
476	Phosphorylation	SKMAAADSVQQRRQY CHHHHHHHHHHHHHH	19.66	25521595
492	Phosphorylation	RQNQQSSSDSGSSST HHHHHCCCCCCCCCC	40.83	29895711
496	Phosphorylation	QSSSDSGSSSTSEDE HCCCCCCCCCCCCCC	25.68	27555448
497	Phosphorylation	SSSDSGSSSTSEDER CCCCCCCCCCCCCCC	40.95	23684622
500	Phosphorylation	DSGSSSTSEDERPKR CCCCCCCCCCCCCCC	45.02	25521595
522	Phosphorylation	VGRRRRHSPSRSASP HHCCCCCCCCCCCCC	23.82	27087446
524	Phosphorylation	RRRRHSPSRSASPSP CCCCCCCCCCCCCCC	41.71	27087446
526	Phosphorylation	RRHSPSRSASPSPRK CCCCCCCCCCCCCCC	37.12	27087446
528	Phosphorylation	HSPSRSASPSPRKRQ CCCCCCCCCCCCCCC	27.45	27087446
530	Phosphorylation	PSRSASPSPRKRQKE CCCCCCCCCCCCCCC	34.54	27087446
538	Phosphorylation	PRKRQKETSPRMQMG CCCCCCCCCCCCCCH	51.58	26745281
539	Phosphorylation	RKRQKETSPRMQMGK CCCCCCCCCCCCCHH	16.17	26745281
550	Phosphorylation	QMGKRWQSPVTKSSR CCHHHCCCCCCHHHH	17.87	24925903
553	Phosphorylation	KRWQSPVTKSSRRRR HHCCCCCCHHHHCCC	28.70	24925903
555	Phosphorylation	WQSPVTKSSRRRRSP CCCCCCHHHHCCCCC	21.51	22807455
561	Phosphorylation	KSSRRRRSPSPPPAR HHHHCCCCCCCCCHH	28.11	25521595
563	Phosphorylation	SRRRRSPSPPPARRR HHCCCCCCCCCHHCC	51.81	25521595
572	Phosphorylation	PPARRRRSPSPAPPP CCHHCCCCCCCCCCC	28.11	18388127
574	Phosphorylation	ARRRRSPSPAPPPPP HHCCCCCCCCCCCCC	34.63	18388127
591	Phosphorylation	PPPRRRRSPTPPPRR CCCCCCCCCCCCCCC	31.17	25521595
593	Phosphorylation	PRRRRSPTPPPRRRT CCCCCCCCCCCCCCC	50.07	25521595
600	Phosphorylation	TPPPRRRTPSPPPRR CCCCCCCCCCCCCCC	26.72	25521595
602	Phosphorylation	PPRRRTPSPPPRRRS CCCCCCCCCCCCCCC	49.80	25521595
609	Phosphorylation	SPPPRRRSPSPRRYS CCCCCCCCCCCCCCC	28.11	23737553
611	Phosphorylation	PPRRRSPSPRRYSPP CCCCCCCCCCCCCCC	32.08	23737553
615	Phosphorylation	RSPSPRRYSPPIQRR CCCCCCCCCCCCCCC	27.15	25521595
616	Phosphorylation	SPSPRRYSPPIQRRY CCCCCCCCCCCCCCC	23.53	18388127
623	Phosphorylation	SPPIQRRYSPSPPPK CCCCCCCCCCCCCCC	27.42	25521595
624	Phosphorylation	PPIQRRYSPSPPPKR CCCCCCCCCCCCCCC	19.65	18388127
626	Phosphorylation	IQRRYSPSPPPKRRT CCCCCCCCCCCCCCC	44.06	18388127
633	Phosphorylation	SPPPKRRTASPPPPP CCCCCCCCCCCCCCC	35.20	18388127
635	Phosphorylation	PPKRRTASPPPPPKR CCCCCCCCCCCCCCC	37.01	18388127
645	Phosphorylation	PPPKRRASPSPPPKR CCCCCCCCCCCCCCC	24.89	25521595
647	Phosphorylation	PKRRASPSPPPKRRV CCCCCCCCCCCCCCC	47.76	25521595
655	Phosphorylation	PPPKRRVSHSPPPKQ CCCCCCCCCCCCCCC	19.21	25521595
657	Phosphorylation	PKRRVSHSPPPKQRS CCCCCCCCCCCCCCC	31.43	25521595
664	Phosphorylation	SPPPKQRSPTVTKRR CCCCCCCCCCCCCCC	23.56	25521595
666	Phosphorylation	PPKQRSPTVTKRRSP CCCCCCCCCCCCCCC	41.89	25521595
668	Phosphorylation	KQRSPTVTKRRSPSL CCCCCCCCCCCCCCC	22.70	25159016
672	Phosphorylation	PTVTKRRSPSLSSKH CCCCCCCCCCCCCCC	23.91	25521595
674	Phosphorylation	VTKRRSPSLSSKHRK CCCCCCCCCCCCCCC	41.97	27087446
676	Phosphorylation	KRRSPSLSSKHRKGS CCCCCCCCCCCCCCC	41.50	22802335
677	Phosphorylation	RRSPSLSSKHRKGSS CCCCCCCCCCCCCCC	37.46	22802335
683	Phosphorylation	SSKHRKGSSPGRSTR CCCCCCCCCCCCCCC	36.07	23375375
684	Phosphorylation	SKHRKGSSPGRSTRE CCCCCCCCCCCCCCH	39.79	27717184
688	Phosphorylation	KGSSPGRSTREARSP CCCCCCCCCCHHCCC	37.42	23375375
689	Phosphorylation	GSSPGRSTREARSPQ CCCCCCCCCHHCCCC	31.03	23375375
694	Phosphorylation	RSTREARSPQPNKRH CCCCHHCCCCCCCCC	34.63	25521595
702	Phosphorylation	PQPNKRHSPSPRPRA CCCCCCCCCCCCCCC	30.98	25521595
704	Phosphorylation	PNKRHSPSPRPRAPQ CCCCCCCCCCCCCCC	36.23	25521595
712	Phosphorylation	PRPRAPQTSSPPPVR CCCCCCCCCCCCCCC	30.07	25521595
713	Phosphorylation	RPRAPQTSSPPPVRR CCCCCCCCCCCCCCC	35.28	24925903
714	Phosphorylation	PRAPQTSSPPPVRRG CCCCCCCCCCCCCCC	44.83	24925903
723	Phosphorylation	PPVRRGASASPQGRQ CCCCCCCCCCCCCCC	31.91	18388127
725	Phosphorylation	VRRGASASPQGRQSP CCCCCCCCCCCCCCC	18.43	18388127
731	Phosphorylation	ASPQGRQSPSPSTRP CCCCCCCCCCCCCCC	26.45	18388127
733	Phosphorylation	PQGRQSPSPSTRPIR CCCCCCCCCCCCCCC	36.41	25521595
735	Phosphorylation	GRQSPSPSTRPIRRV CCCCCCCCCCCCCCC	41.19	25521595
736	Phosphorylation	RQSPSPSTRPIRRVS CCCCCCCCCCCCCCC	43.80	27087446
743	Phosphorylation	TRPIRRVSRTPEPKK CCCCCCCCCCCCCHH	28.73	23684622
745	Phosphorylation	PIRRVSRTPEPKKIK CCCCCCCCCCCHHHH	25.21	25521595
766	Phosphorylation	QRNIRRVSKSPKADS HHHHHHHHCCCCHHH	26.13	19367708
768	Phosphorylation	NIRRVSKSPKADSLS HHHHHHCCCCHHHHH	24.91	27149854
779	Phosphorylation	DSLSRAASPSPQSVR HHHHCCCCCCHHHHH	25.56	27087446
781	Phosphorylation	LSRAASPSPQSVRRV HHCCCCCCHHHHHHH	32.83	27087446
784	Phosphorylation	AASPSPQSVRRVSSS CCCCCHHHHHHHCCC	22.45	27087446
787	Phosphorylation	PSPQSVRRVSSSRSV CCHHHHHHHCCCCCC	30.43	24719451
789	Phosphorylation	PQSVRRVSSSRSVSG HHHHHHHCCCCCCCC	22.30	27087446
790	Phosphorylation	QSVRRVSSSRSVSGS HHHHHHCCCCCCCCC	27.24	27087446
791	Phosphorylation	SVRRVSSSRSVSGSP HHHHHCCCCCCCCCC	22.52	27087446
793	Phosphorylation	RRVSSSRSVSGSPEP HHHCCCCCCCCCCCC	23.68	25521595
795	Phosphorylation	VSSSRSVSGSPEPAA HCCCCCCCCCCCCHH	34.50	25521595
797	Phosphorylation	SSRSVSGSPEPAAKK CCCCCCCCCCCHHCC	20.70	25521595
799	Phosphorylation	RSVSGSPEPAAKKPP CCCCCCCCCHHCCCC	49.63	24719451
809	Phosphorylation	AKKPPAPPSPVQSQS HCCCCCCCCCCCCCC	54.06	24719451
810	Phosphorylation	KKPPAPPSPVQSQSP CCCCCCCCCCCCCCC	36.32	18388127
813	Phosphorylation	PAPPSPVQSQSPSTN CCCCCCCCCCCCCCC	38.85	24719451
814	Phosphorylation	APPSPVQSQSPSTNW CCCCCCCCCCCCCCC	32.62	18388127
816	Phosphorylation	PSPVQSQSPSTNWSP CCCCCCCCCCCCCCC	26.51	18388127
818	Phosphorylation	PVQSQSPSTNWSPAV CCCCCCCCCCCCCCC	39.35	24925903
819	Phosphorylation	VQSQSPSTNWSPAVP CCCCCCCCCCCCCCC	44.05	24925903
822	Phosphorylation	QSPSTNWSPAVPAKK CCCCCCCCCCCCHHH	12.68	18388127
832	Phosphorylation	VPAKKAKSPTPSLSP CCHHHCCCCCCCCCC	38.58	25521595
834	Phosphorylation	AKKAKSPTPSLSPAR HHHCCCCCCCCCCCC	32.38	25521595
836	Phosphorylation	KAKSPTPSLSPARNS HCCCCCCCCCCCCCC	43.91	26824392
838	Phosphorylation	KSPTPSLSPARNSDQ CCCCCCCCCCCCCCC	22.35	25521595
843	Phosphorylation	SLSPARNSDQEGGGK CCCCCCCCCCCCCCC	34.81	27087446
872	Phosphorylation	KHKKHKKHKKEKAVT HHHHHHHHHHHHCEE	51.75	24719451
879	Phosphorylation	HKKEKAVTIATPATA HHHHHCEEEECHHHH	15.11	27180971
882	Phosphorylation	EKAVTIATPATAAPA HHCEEEECHHHHCCH	15.03	30352176
885	Phosphorylation	VTIATPATAAPAAVS EEEECHHHHCCHHHH	25.26	25777480
890	Phosphorylation	PATAAPAAVSAATTT HHHHCCHHHHHHCCC	8.50	24719451
892	Phosphorylation	TAAPAAVSAATTTSA HHCCHHHHHHCCCCH	13.88	25777480
895	Phosphorylation	PAAVSAATTTSAQEE CHHHHHHCCCCHHHC	30.26	25777480
896	Phosphorylation	AAVSAATTTSAQEEP HHHHHHCCCCHHHCC	17.64	25777480
897	Phosphorylation	AVSAATTTSAQEEPA HHHHHCCCCHHHCCC	20.08	25777480
898	Phosphorylation	VSAATTTSAQEEPAA HHHHCCCCHHHCCCC	26.34	26824392
913	Phosphorylation	APEPRKETESEAEDD CCCCCCCCCCHHCCC	48.09	27087446
915	Phosphorylation	EPRKETESEAEDDNL CCCCCCCCHHCCCCH	49.91	27087446
936	Phosphorylation	LREKALRSMRKAQVS HHHHHHHHHHHHHCC	24.64	-
943	Phosphorylation	SMRKAQVSPQS---- HHHHHHCCCCC----	12.73	25521595
946	Phosphorylation	KAQVSPQS------- HHHCCCCC-------	45.64	24453211

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SRRM1_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SRRM1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SRRM1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SRRM1_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SRRM1_MOUSE

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large scale localization of protein phosphorylation by use ofelectron capture dissociation mass spectrometry."; Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.; Mol. Cell. Proteomics 8:904-912(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-220; SER-260; SER-572;SER-574; SER-616; SER-714; SER-723; SER-725; SER-731; SER-810;SER-816; SER-822; THR-913 AND SER-915, AND MASS SPECTROMETRY.	19131326 [Abstract]
"The phagosomal proteome in interferon-gamma-activated macrophages."; Trost M., English L., Lemieux S., Courcelles M., Desjardins M.,Thibault P.; Immunity 30:143-154(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-260; SER-387; SER-427;SER-429; SER-694; SER-702; SER-704; SER-779 AND SER-781, AND MASSSPECTROMETRY.	19144319 [Abstract]
"Solid tumor proteome and phosphoproteome analysis by high resolutionmass spectrometry."; Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J.,Faessler R., Mann M.; J. Proteome Res. 7:5314-5326(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-207; SER-209; SER-211;SER-220; SER-260; SER-387; SER-389; SER-391; THR-404; SER-427;SER-429; SER-448; SER-461; SER-463; SER-561; SER-563; SER-572;SER-574; SER-591; THR-593; THR-600; SER-602; SER-624; SER-626;THR-633; SER-635; SER-645; SER-647; SER-655; SER-657; SER-672;SER-702; SER-704; SER-723; SER-725; SER-766; SER-779; SER-781;SER-784; SER-793; SER-795; SER-797; SER-832 AND SER-915, AND MASSSPECTROMETRY.	19367708 [Abstract]
"Specific phosphopeptide enrichment with immobilized titanium ionaffinity chromatography adsorbent for phosphoproteome analysis."; Zhou H., Ye M., Dong J., Han G., Jiang X., Wu R., Zou H.; J. Proteome Res. 7:3957-3967(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-387; SER-391; SER-427;SER-429; SER-448; SER-616; SER-624; SER-626; SER-635; SER-810 ANDSER-814, AND MASS SPECTROMETRY.	18630941 [Abstract]
"Large-scale phosphorylation analysis of mouse liver."; Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-461; SER-463; SER-723;SER-725; SER-731; SER-733; SER-810; SER-816; SER-822 AND SER-915, ANDMASS SPECTROMETRY.	17242355 [Abstract]
"Qualitative and quantitative analyses of protein phosphorylation innaive and stimulated mouse synaptosomal preparations."; Munton R.P., Tweedie-Cullen R., Livingstone-Zatchej M., Weinandy F.,Waidelich M., Longo D., Gehrig P., Potthast F., Rutishauser D.,Gerrits B., Panse C., Schlapbach R., Mansuy I.M.; Mol. Cell. Proteomics 6:283-293(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-572, AND MASSSPECTROMETRY.	17114649 [Abstract]
"A differential phosphoproteomic analysis of retinoic acid-treated P19cells."; Smith J.C., Duchesne M.A., Tozzi P., Ethier M., Figeys D.; J. Proteome Res. 6:3174-3186(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-461; SER-463; SER-591;THR-593; THR-600; SER-602; THR-913 AND SER-915, AND MASS SPECTROMETRY.	17622165 [Abstract]
"Protein phosphorylation and expression profiling by Yin-yangmultidimensional liquid chromatography (Yin-yang MDLC) massspectrometry."; Dai J., Jin W.-H., Sheng Q.-H., Shieh C.-H., Wu J.-R., Zeng R.; J. Proteome Res. 6:250-262(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-461, AND MASSSPECTROMETRY.	17203969 [Abstract]
"Phosphoproteomic analysis of the developing mouse brain."; Ballif B.A., Villen J., Beausoleil S.A., Schwartz D., Gygi S.P.; Mol. Cell. Proteomics 3:1093-1101(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-572 AND SER-574, ANDMASS SPECTROMETRY.	15345747 [Abstract]