SRP54_MOUSE - dbPTM
SRP54_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SRP54_MOUSE
UniProt AC P14576
Protein Name Signal recognition particle 54 kDa protein
Gene Name Srp54
Organism Mus musculus (Mouse).
Sequence Length 504
Subcellular Localization Nucleus speckle. Cytoplasm.
Protein Description Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein)..
Protein Sequence MVLADLGRKITSALRSLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVSNAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIEGLIDKVNELKLDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQMVKKMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAGNMKGMMGFNNM
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
16PhosphorylationKITSALRSLSNATII
HHHHHHHHHHCCCCC		36.6823984901
18PhosphorylationTSALRSLSNATIINE
HHHHHHHHCCCCCCH		26.1828418008
21PhosphorylationLRSLSNATIINEEVL
HHHHHCCCCCCHHHH		27.0026643407
50UbiquitinationDVNIKLVKQLRENVK
HHHHHHHHHHHHHHH		54.7922790023
71UbiquitinationEMASGLNKRKMIQHA
HHHHCCCHHHHHHHH		59.4422790023
259UbiquitinationGHAKGGGALSAVAAT
CCCCCCCHHHHHHHC		11.1327667366
268PhosphorylationSAVAATKSPIIFIGT
HHHHHCCCCEEEEEC		19.58-
309UbiquitinationGLIDKVNELKLDDNE
HHHHHHHHCCCCCCH		50.7127667366
311AcetylationIDKVNELKLDDNEAL
HHHHHHCCCCCCHHH		43.637720365
311UbiquitinationIDKVNELKLDDNEAL
HHHHHHCCCCCCHHH		43.6322790023
321UbiquitinationDNEALIEKLKHGQFT
CCHHHHHHHHCCCEE		56.7022790023
323UbiquitinationEALIEKLKHGQFTLR
HHHHHHHHCCCEEHH		57.6722790023
374UbiquitinationESMARLKKLMTIMDS
HHHHHHHHHHHHHHH		48.3522790023
398MalonylationDGAKVFSKQPGRIQR
CCCEECCCCCCCEEE		49.3926320211
398UbiquitinationDGAKVFSKQPGRIQR
CCCEECCCCCCCEEE		49.3927667366
426UbiquitinationELLTQYTKFAQMVKK
HHHHHHHHHHHHHHH		33.4922790023
432MalonylationTKFAQMVKKMGGIKG
HHHHHHHHHCCCCCC		31.5326320211
438AcetylationVKKMGGIKGLFKGGD
HHHCCCCCCHHCCCC		53.497713279
442AcetylationGGIKGLFKGGDMSKN
CCCCCHHCCCCCCCC		68.0119858473
448AcetylationFKGGDMSKNVSQSQM
HCCCCCCCCCCHHHH		55.5219858481
448UbiquitinationFKGGDMSKNVSQSQM
HCCCCCCCCCCHHHH		55.5222790023
451PhosphorylationGDMSKNVSQSQMAKL
CCCCCCCCHHHHHHH		33.2422324799
453PhosphorylationMSKNVSQSQMAKLNQ
CCCCCCHHHHHHHHH		17.8922324799
457UbiquitinationVSQSQMAKLNQQMAK
CCHHHHHHHHHHHHH		42.5022790023
464UbiquitinationKLNQQMAKMMDPRVL
HHHHHHHHHCCHHHH		29.4322790023
496UbiquitinationQGAAGNMKGMMGFNN
HHCCCCCCCCCCCCC		47.8822790023
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SRP54_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SRP54_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SRP54_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of SRP54_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SRP54_MOUSE

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Related Literatures of Post-Translational Modification

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