dbPTM

SRB4D_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SRB4D_HUMAN
UniProt AC	Q8WTU2
Protein Name	Scavenger receptor cysteine-rich domain-containing group B protein {ECO:0000303\|PubMed:12466895, ECO:0000312\|HGNC:HGNC:14461}
Gene Name	SSC4D {ECO:0000312\|HGNC:HGNC:14461}
Organism	Homo sapiens (Human).
Sequence Length	575
Subcellular Localization	Secreted .
Protein Description
Protein Sequence	MHKEAEMLIGPQLDEKRWGWRLGDGSAAPPFLPQALSFLLLLPLASALQPTPLPFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
178	O-linked_Glycosylation	LTSRAPPTTLPNGKS HCCCCCCCCCCCCCC	39.65	OGP
312	O-linked_Glycosylation	REDWAWQTDPSATGV CCCCCCCCCCCCCCC	38.89	OGP
331	O-linked_Glycosylation	SRETALLTTAAWAAG CHHHHHHHHHHHHCC	18.42	OGP
332	O-linked_Glycosylation	RETALLTTAAWAAGK HHHHHHHHHHHHCCC	17.85	OGP
496	Phosphorylation	YLGQRWGTVCDDAWD EECCCCCCCCCCHHH	15.82	30257219
565	Phosphorylation	DAHNCDHSEDASVLC CCCCCCCCCCCCEEC	24.74	30576142
569	Phosphorylation	CDHSEDASVLCQPS- CCCCCCCCEECCCC-	28.13	30576142
575	Phosphorylation	ASVLCQPS------- CCEECCCC-------	27.29	30576142

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SRB4D_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SRB4D_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SRB4D_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SRB4D_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SRB4D_HUMAN

Related Literatures of Post-Translational Modification