SRAC1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SRAC1_MOUSE
• UniProt AC: Q3U213
• Protein Name: Protein SERAC1
• Gene Name: Serac1
• Organism: Mus musculus (Mouse).
• Sequence Length: 654
• Subcellular Localization: Membrane ; Single-pass membrane protein . Endoplasmic reticulum. Mitochondrion. Localizes at the endoplasmic reticulum and at the endoplasmic reticulum-mitochondria interface..
• Protein Description: Plays an important role in the phosphatidylglycerol remodeling that is essential for both mitochondrial function and intracellular cholesterol trafficking. May catalyze the remodeling of phosphatidylglycerol and be involved in the transacylation-acylation reaction to produce phosphatidylglycerol-36:1. May be involved in bis(monoacylglycerol)phosphate biosynthetic pathway (By similarity)..
• Protein Sequence: MSLAAYCVICCRRIGSFAPRSKSRTPWRNIRNIIRFTGSLIVGGSLFITYEVLALKKSLMLDTQVVEREKMKSYIYVHKAPVDRLDNRGIVWQARKELHRAVRKLLAAAAKVLRSPFADSFSTVDIEDHDCAVWLLLRKSREDDLAARLQAVREMSEAHHWHDYQYRIIAQACDPRTLIGLARSKESDLRFFLPPPPLPSLKEDSSTEEELRHLLASLPQTELDECLQYFTSLALSESSQSLAAQKGGLWCFGGNGLPYAESFGKVPSATVEMFCLEAIVKHSEIPSHCDHIEAGGGLQLLQRLYQLHKDCPKVQRNVMRIIGNMALNEHLHPAIVHSGWVSLMAEALKSSHIMEASHAARTLANLDRETVGEKYQDGVYVLHPQCRTSQPIKADVLFIHGLMGAAFKTWRQHDSQRALTESAVVDEDRYTTCWPKTWLAKDCPSLRIISVEYDTSLSDWRARCPMERKSIAFRSNELLSKLRAAGVGDRPMIWISHSMGGLLVKKMLLEASKKPELNALINNTRGIIFYSVPHHGSRLAEYSVNIRYLLFPSLEVKELSKDSPALKTLQDDFLEFAKDKNFQVLNFVETQPTFIGSMIKLHVVPVESADLGIGDLIPVDVNHLNICKPKTKDAFLYQRTLQFICETLARDLEN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
57	Ubiquitination	YEVLALKKSLMLDTQ HHHHHHHHHHHCCCH	50.07	-
70	Ubiquitination	TQVVEREKMKSYIYV CHHHCHHHHHHEEEE	58.82	-
321	Phosphorylation	VQRNVMRIIGNMALN HHHHHHHHHHHHHHH	2.27	-
351	Phosphorylation	MAEALKSSHIMEASH HHHHHHHCCHHHHHH	18.55	23140645
470	Phosphorylation	RCPMERKSIAFRSNE HCCCCHHCHHHHHHH	25.93	28059163

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SRAC1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SRAC1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SRAC1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SRAC1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.