SQOR_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SQOR_MOUSE
• UniProt AC: Q9R112
• Protein Name: Sulfide:quinone oxidoreductase, mitochondrial {ECO:0000305}
• Gene Name: Sqor {ECO:0000250|UniProtKB:Q9Y6N5}
• Organism: Mus musculus (Mouse).
• Sequence Length: 450
• Subcellular Localization: Mitochondrion .
• Protein Description: Catalyzes the oxidation of hydrogen sulfide with the help of a quinone, such as ubiquinone, giving rise to thiosulfate and ultimately to sulfane (molecular sulfur) atoms. Requires an additional electron acceptor; can use sulfite, sulfide or cyanide (in vitro)..
• Protein Sequence: MAPLVTVVSSPRARLFACFLRLGTQQAGPLQLHTGACCTAKNHYEVLVLGGGAGGITMATRMKRRVGAENVAIVEPSERHFYQPIWTLVGAGAKELSLSVRSTLSVIPSGVQWIQDRVAELNPDENCIRTDSGKEISYRYLIIALGIQLDYEKIKGLPEGFAYPKIGSNYSVKTVEKTWKALQGFKEGNALFTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRPKANIIFNTALGTIFGVKKYADALQEIIRERDVSVNYKHNLIEVRPDKQEAVFEILDKPGETHVIPYEMLHVTPPMSAPDVLKRSPVADSAGWVDVDKETLQHKKYPNVFGIGDCTNLPTSKTAAAVAAQSGILDRTMCLIMKNQRPIKKYDGYTSCPLVTGYNRVILAEFDYTAQPLETFPFDQSKERITMYLMKADMMPFLYWNMMLRGYWGGPAFLRKLFHLGMN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MAPLVTVVSSPRA --CCCCEEEECCHHH		21183079
9	Phosphorylation	APLVTVVSSPRARLF CCCEEEECCHHHHHH		22817900
10	Phosphorylation	PLVTVVSSPRARLFA CCEEEECCHHHHHHH		22817900
127	S-nitrosocysteine	ELNPDENCIRTDSGK HHCCCCCEEECCCCC		-
127	S-palmitoylation	ELNPDENCIRTDSGK HHCCCCCEEECCCCC		28526873
134	Succinylation	CIRTDSGKEISYRYL EEECCCCCEEEHHHH		23806337
134	Acetylation	CIRTDSGKEISYRYL EEECCCCCEEEHHHH		23576753
155	Acetylation	QLDYEKIKGLPEGFA CCCHHHHCCCCCCCC		22733758
173	Acetylation	IGSNYSVKTVEKTWK CCCCCEEEEHHHHHH		23576753
173	Succinylation	IGSNYSVKTVEKTWK CCCCCEEEEHHHHHH		23806337
173	Malonylation	IGSNYSVKTVEKTWK CCCCCEEEEHHHHHH		32601280
177	Acetylation	YSVKTVEKTWKALQG CEEEEHHHHHHHHCC		23201123
177	Malonylation	YSVKTVEKTWKALQG CEEEEHHHHHHHHCC		26320211
186	Acetylation	WKALQGFKEGNALFT HHHHCCCCCCCEEEE		23576753
260	Acetylation	RDVSVNYKHNLIEVR CCCCCCCCCCCEEEC		23954790
320	Acetylation	AGWVDVDKETLQHKK CCEEECCHHHHCCCC		23201123
327	Acetylation	KETLQHKKYPNVFGI HHHHCCCCCCCCCCC		22733758
338	Phosphorylation	VFGIGDCTNLPTSKT CCCCCCCCCCCCHHH		27742792
342	Phosphorylation	GDCTNLPTSKTAAAV CCCCCCCCHHHHHHH		27742792
343	Phosphorylation	DCTNLPTSKTAAAVA CCCCCCCHHHHHHHH		27742792
345	Phosphorylation	TNLPTSKTAAAVAAQ CCCCCHHHHHHHHHH		24719451
361	S-palmitoylation	GILDRTMCLIMKNQR CCCHHHHHHHHCCCC		28526873
361	S-nitrosocysteine	GILDRTMCLIMKNQR CCCHHHHHHHHCCCC		-
365	Acetylation	RTMCLIMKNQRPIKK HHHHHHHCCCCCCCC		23201123
379	S-palmitoylation	KYDGYTSCPLVTGYN CCCCCCCCCCCCCCC		28526873

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SQOR_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SQOR_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SQOR_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SQOR_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.