SPT21_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SPT21_HUMAN
• UniProt AC: Q7Z572
• Protein Name: Spermatogenesis-associated protein 21
• Gene Name: SPATA21
• Organism: Homo sapiens (Human).
• Sequence Length: 469
• Protein Description: Involved in the differentiation of haploid spermatids..
• Protein Sequence: MDNRNTQMYTEEEKTVNPFLPSTPGPKKAKGGGEAVETHPAPGPLPPPEVRDIGERREPDRAQQQPQKPAVAAGTQSLGNFRQGFMKCLLEVEKMEASHRRASKARSQTAQKSPRTLTPVPTSAPSLPQTPASVPASGPSWARLPAPGPEPAPMGAPVPTSMPCPVLLGPALDLGWRRMELLHQSSERTLSYAKARQEPEEQSLQKLYQNREKSEEQLTLKQEEAFRSYFEIFNGPGEVDAQSLKNILLLMGFSVTLAQVEDALMSADVNGDGRVDFKDFLAVMTDTRRFFCSVEQNALSDMAPHNPHTLLFEILSLLVEMLALPEAVLEEITNYYQKKLKEGTCKAQEMEAAVGRLRLQKLPYNPQQEESSEVPERKVLSILSRLKQQNYAPNLQSPYAQVPCILLCPQLDKKMVRRQPSNHYALDQCTPPGLDPDIRSPFFQSGSQGNREHNSDSRKWLSSVPARTH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MDNRNTQMYTEEE --CCCCCCCCCCCCC	16.10	29083192
9	Phosphorylation	DNRNTQMYTEEEKTV CCCCCCCCCCCCCCC	10.94	29083192
10	Phosphorylation	NRNTQMYTEEEKTVN CCCCCCCCCCCCCCC	31.42	29083192
15	Phosphorylation	MYTEEEKTVNPFLPS CCCCCCCCCCCCCCC	28.88	29083192
22	Phosphorylation	TVNPFLPSTPGPKKA CCCCCCCCCCCCCCC	49.75	29083192
23	Phosphorylation	VNPFLPSTPGPKKAK CCCCCCCCCCCCCCC	30.26	29083192
109	Phosphorylation	ASKARSQTAQKSPRT HHHHHHHHCCCCCCC	32.10	-
185	Phosphorylation	RMELLHQSSERTLSY HHHHHHHHHHHHHHH	24.34	23401153
186	Phosphorylation	MELLHQSSERTLSYA HHHHHHHHHHHHHHH	25.24	23401153
192	Phosphorylation	SSERTLSYAKARQEP HHHHHHHHHHHHCCH	18.42	23401153
208	Phosphorylation	EQSLQKLYQNREKSE HHHHHHHHHCHHHCH	15.69	28796482
381	Phosphorylation	VPERKVLSILSRLKQ CCHHHHHHHHHHHHH	25.19	24719451
384	Phosphorylation	RKVLSILSRLKQQNY HHHHHHHHHHHHCCC	33.62	24719451
447	Phosphorylation	SPFFQSGSQGNREHN CCCCCCCCCCCCCCC	39.91	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SPT21_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SPT21_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SPT21_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of SPT21_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.