SPT20_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SPT20_MOUSE
• UniProt AC: Q80YT5
• Protein Name: Spermatogenesis-associated protein 20
• Gene Name: Spata20
• Organism: Mus musculus (Mouse).
• Sequence Length: 790
• Subcellular Localization: Secreted .
• Protein Description: May play a role in fertility regulation..
• Protein Sequence: MSHHSSPPPKHKGEHKGHGLPRGSERGSSSRDKDRSATTVSSSAPMPAGGKSSRTNCPPPAPPKTVNRLINEKSPYLLQHAYNPVDWYPWGQEAFDKAKKENKPIFLSVGYSTCHWCHMMEEESFQNEEIGRLLNENFICVMVDREERPDVDKVYMTFVQATSSGGGWPMNVWLTPGLQPFVGGTYFPPEDGLTRVGFRTVLMRICDQWKLNKNTLLENSQRVTTALLARSEISVGDRQIPASAATMNSRCFQQLDEGYDEEYGGFAEAPKFPTPVILNFLFSYWLSHRLTQDGSRAQQMALHTLKMMANGGIQDHVGQGFHRYSTDRQWHIPHFEKMLYDQAQLSVVYTQAFQISGDEFYADVAKGILQYVTRTLSHRSGGFYSAEDADSPPERGMKPQEGAYYVWTVKEVQQLLPEPVVGASEPLTSGQLLMKHYGLSEVGNINSSQDPNGELHGQNVLMVRYSLELTAARYGLEVEAVRALLNTGLEKLFQARKHRPKAHLDNKMLAAWNGLMVSGFAVTGAALGMEKLVAQATSGAKFLKRHMFDVSSGRLKRTCYAGTGGTVEQSNPPCWGFLEDYAFVVRGLLDLYEASQESSWLEWALRLQDTQDKLFWDPRGGGYFCSEAELGADLPLRLKDDQDGAEPSANSVSAHNLLRLHSFTGHKDWMDKCVCLLTAFSERMRRVPVALPEMVRTLSAQQQTLKQIVICGDPQAKDTKALLQCVHSIYVPNKVLILADGDPSSFLSRQLPFLSSLRRVEDRATVYIFENQACSMPITDPCELRKLLHQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MSHHSSPPPKHK ---CCCCCCCCCCCC	38.83	-
24	Phosphorylation	GHGLPRGSERGSSSR CCCCCCCCCCCCCCC	25.96	-
38	Phosphorylation	RDKDRSATTVSSSAP CCCCCCCCEECCCCC	29.04	22817900
39	Phosphorylation	DKDRSATTVSSSAPM CCCCCCCEECCCCCC	20.36	22817900
64	Ubiquitination	CPPPAPPKTVNRLIN CCCCCCCHHHHHHHH	65.14	-
213	Ubiquitination	CDQWKLNKNTLLENS HHHHCCCCCCHHHHH	62.84	-
246	Phosphorylation	QIPASAATMNSRCFQ CCCCCHHHHCHHHHH	19.32	28576409
523	Phosphorylation	MVSGFAVTGAALGME EECCEEHHHHHHCHH	20.06	26239621
537	Phosphorylation	EKLVAQATSGAKFLK HHHHHHHHHHHHHHH	18.66	26239621
538	Phosphorylation	KLVAQATSGAKFLKR HHHHHHHHHHHHHHH	39.51	26239621
613	Ubiquitination	RLQDTQDKLFWDPRG HCHHCCCHHCCCCCC	35.45	-
648	Phosphorylation	DQDGAEPSANSVSAH CCCCCCCCCCCCCHH	31.42	26643407
651	Phosphorylation	GAEPSANSVSAHNLL CCCCCCCCCCHHHHH	19.71	26643407
653	Phosphorylation	EPSANSVSAHNLLRL CCCCCCCCHHHHHHH	24.51	26643407
697	Phosphorylation	ALPEMVRTLSAQQQT CHHHHHHHHCHHHHH	17.41	-
699	Phosphorylation	PEMVRTLSAQQQTLK HHHHHHHCHHHHHHH	24.34	-
704	Phosphorylation	TLSAQQQTLKQIVIC HHCHHHHHHHHEEEC	31.42	-
717	Ubiquitination	ICGDPQAKDTKALLQ ECCCCCCHHHHHHHH	61.76	-
755	Phosphorylation	SRQLPFLSSLRRVED HHCCHHHHHCCCCCC	27.92	25159016
756	Phosphorylation	RQLPFLSSLRRVEDR HCCHHHHHCCCCCCC	28.21	23140645

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SPT20_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SPT20_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SPT20_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SPT20_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.