SPS1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SPS1_MOUSE
• UniProt AC: Q8BH69
• Protein Name: Selenide, water dikinase 1
• Gene Name: Sephs1
• Organism: Mus musculus (Mouse).
• Sequence Length: 392
• Subcellular Localization: Cell membrane. Nucleus membrane.
• Protein Description: Synthesizes selenophosphate from selenide and ATP..
• Protein Sequence: MSTRESFNPETYELDKSFRLTRFTELKGTGCKVPQDVLQKLLESLQENHFQEDEQFLGAVMPRLGIGMDTCVIPLRHGGLSLVQTTDYIYPIVDDPYMMGRIACANVLSDLYAMGVTECDNMLMLLGVSNKMTDRERDKVIPLIIQGFKDAAEEAGTSVTGGQTVLNPWIVLGGVATTVCQPNEFIMPDNAVPGDVLVLTKPLGTQVAVAVHQWLDIPEKWNKIKLVVTQEDVELAYQEAMMNMARLNRTAAGLMHTFNAHAATDITGFGILGHAQNLAKQQRNEVSFVIHNLPVLAKMAAVSKACGNMFGLMHGTCPETSGGLLICLPREQAARFCAEIKSPKYGEGHQAWIIGIVEKGNRTARIIDKPRIIEVAPQVATQNVNPTPGATS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSTRESFNP ------CCCCCCCCH	35.85	-
2	Phosphorylation	------MSTRESFNP ------CCCCCCCCH	35.85	29176673
3	Phosphorylation	-----MSTRESFNPE -----CCCCCCCCHH	36.84	29176673
6	Phosphorylation	--MSTRESFNPETYE --CCCCCCCCHHHHH	27.34	29176673
16	Acetylation	PETYELDKSFRLTRF HHHHHHCCEEEEEEC	65.21	23954790
16	Ubiquitination	PETYELDKSFRLTRF HHHHHHCCEEEEEEC	65.21	-
17	Phosphorylation	ETYELDKSFRLTRFT HHHHHCCEEEEEECE	18.44	28833060
27	Acetylation	LTRFTELKGTGCKVP EEECEECCCCCCCCC	48.47	23806337
27	Malonylation	LTRFTELKGTGCKVP EEECEECCCCCCCCC	48.47	26320211
139	Ubiquitination	MTDRERDKVIPLIIQ CCHHHHHCHHHHHHH	48.57	-
345	Phosphorylation	AEIKSPKYGEGHQAW HHCCCCCCCCCCEEE	24.64	29514104
387	Phosphorylation	ATQNVNPTPGATS-- CCCCCCCCCCCCC--	29.20	25293948
391	Phosphorylation	VNPTPGATS------ CCCCCCCCC------	40.67	26643407
392	Phosphorylation	NPTPGATS------- CCCCCCCC-------	37.38	25521595

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SPS1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SPS1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SPS1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SPS1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.