dbPTM

SPS1_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SPS1_DROME
UniProt AC	O18373
Protein Name	Selenide, water dikinase
Gene Name	SelD
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	398
Subcellular Localization
Protein Description	Synthesizes selenophosphate from selenide and ATP. Essential for progression of the cell cycle by controlling the synthesis of selenoproteins. Plays a role in apoptosis and consequently a role in imaginal disk patterning and growth..
Protein Sequence	MSYAADVLNSAHLELHGGGDAELRRPFDPTAHDLDASFRLTRFADLKGRGCKVPQDVLSKLVSALQQDYSAQDQEPQFLNVAIPRIGIGLDCSVIPLRHGGLCLVQTTDFFYPIVDDPYMMGKIACANVLSDLYAMGVTDCDNMLMLLAVSTKMTEKERDVVIPLIMRGFKDSALEAGTTVTGGQSVVNPWCTIGGVASTICQPNEYIVPDNAVVGDVLVLTKPLGTQVAVNAHQWIDQPERWNRIKLVVSEEDVRKAYHRAMNSMARLNRVAARLMHKYNAHGATDITGFGLLGHAQTLAAHQKKDVSFVIHNLPVIAKMAAVAKACGNMFQLLQGHSAETSGGLLICLPREQAAAYCKDIEKQEGYQAWIIGIVEKGNKTARIIDKPRVIEVPAKD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSYAADVLN ------CCHHHHHHH	24.39	19429919
10	Phosphorylation	YAADVLNSAHLELHG HHHHHHHHHCEEECC	16.95	19429919
37	Phosphorylation	TAHDLDASFRLTRFA CHHHHCHHHEEEEHH	15.57	19429919
47	Acetylation	LTRFADLKGRGCKVP EEEHHHHCCCCCCCC	47.30	21791702

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SPS1_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SPS1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SPS1_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SPS1_DROME !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SPS1_DROME

Related Literatures of Post-Translational Modification