SPNXC_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SPNXC_HUMAN
• UniProt AC: Q9NY87
• Protein Name: Sperm protein associated with the nucleus on the X chromosome C {ECO:0000305}
• Gene Name: SPANXC
• Organism: Homo sapiens (Human).
• Sequence Length: 97
• Subcellular Localization: Cytoplasm . Nucleus . Associated with nuclear craters.
• Protein Sequence: MDKQSSAGGVKRSVPCDSNEANEMMPETSSGYSDPQPAPKKLKTSESSTILVVRYRRNVKRTSPEELVNDHARENRINPLQMEEEEFMEIMVEIPAK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MDKQSSAGGVKR ---CCCCCCCCCCCC	28.09	-
6	Phosphorylation	--MDKQSSAGGVKRS --CCCCCCCCCCCCC	28.56	-
13	Phosphorylation	SAGGVKRSVPCDSNE CCCCCCCCCCCCCHH	25.37	25693802
18	Phosphorylation	KRSVPCDSNEANEMM CCCCCCCCHHHHHCC	45.03	25693802
28	Phosphorylation	ANEMMPETSSGYSDP HHHCCCCCCCCCCCC	21.93	25693802
29	Phosphorylation	NEMMPETSSGYSDPQ HHCCCCCCCCCCCCC	32.49	25693802
30	Phosphorylation	EMMPETSSGYSDPQP HCCCCCCCCCCCCCC	62.13	25693802
32	Phosphorylation	MPETSSGYSDPQPAP CCCCCCCCCCCCCCC	52.96	25693802
33	Phosphorylation	PETSSGYSDPQPAPK CCCCCCCCCCCCCCC	53.16	25693802
44	Phosphorylation	PAPKKLKTSESSTIL CCCCCCCCCCCCEEE	33.94	23186163
45	Phosphorylation	APKKLKTSESSTILV CCCCCCCCCCCEEEE	29.93	26091039
47	Phosphorylation	KKLKTSESSTILVVR CCCCCCCCCEEEEEE	32.33	22777824
48	Phosphorylation	KLKTSESSTILVVRY CCCCCCCCEEEEEEE	18.53	23186163
49	Phosphorylation	LKTSESSTILVVRYR CCCCCCCEEEEEEEC	27.84	25693802
62	Phosphorylation	YRRNVKRTSPEELVN ECCCCCCCCHHHHHH	42.80	30266825
63	Phosphorylation	RRNVKRTSPEELVND CCCCCCCCHHHHHHH	34.05	30266825

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SPNXC_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SPNXC_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SPNXC_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of SPNXC_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.