SPIN3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SPIN3_HUMAN
• UniProt AC: Q5JUX0
• Protein Name: Spindlin-3
• Gene Name: SPIN3
• Organism: Homo sapiens (Human).
• Sequence Length: 258
• Protein Description: Exhibits H3K4me3-binding activity..
• Protein Sequence: MKTPFGKAAAGQRSRTGAGHGSVSVTMIKRKAAHKKHRSRPTSQPRGNIVGCRIQHGWKDGDEPLTQWKGTVLDQVPVNPSLYLIKYDGFDCVYGLELHRDERVSSLEVLPNRVASSRISDTHLAEIMVGKAVEHIFETEEGSKNEWRGMVLAQAPVMNTWFYITYEKDPVLYMYQLLDDYKDGDLRILQDSNDSPLAEREPGEVIDSLVGKQVEYAKDDGSKRTGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVKTS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Methylation	------MKTPFGKAA ------CCCCCCCCC	65.98	-
3	Phosphorylation	-----MKTPFGKAAA -----CCCCCCCCCC	23.66	24719451
16	Phosphorylation	AAGQRSRTGAGHGSV CCCCCCCCCCCCCCE	32.41	20068231
22	Phosphorylation	RTGAGHGSVSVTMIK CCCCCCCCEEEEEEE	12.92	20068231
24	Phosphorylation	GAGHGSVSVTMIKRK CCCCCCEEEEEEECH	17.36	20068231
26	Phosphorylation	GHGSVSVTMIKRKAA CCCCEEEEEEECHHH	12.98	20068231
39	Phosphorylation	AAHKKHRSRPTSQPR HHCHHHHCCCCCCCC	42.19	22468782
87	Phosphorylation	PSLYLIKYDGFDCVY CCEEEEEECCCCEEE	17.82	17053785
94	Phosphorylation	YDGFDCVYGLELHRD ECCCCEEEEEEECCC	23.48	-
105	Phosphorylation	LHRDERVSSLEVLPN ECCCCCCCCEEECCC	35.11	-
116	Phosphorylation	VLPNRVASSRISDTH ECCCCHHHCCCCHHH	19.79	24719451
120	Phosphorylation	RVASSRISDTHLAEI CHHHCCCCHHHHHHH	35.03	27050516
122	Phosphorylation	ASSRISDTHLAEIMV HHCCCCHHHHHHHHH	16.40	29759185
182	Ubiquitination	YQLLDDYKDGDLRIL EEEHHHCCCCCEEEE	63.33	22817900
192	Phosphorylation	DLRILQDSNDSPLAE CEEEEECCCCCCCCC	29.58	30266825
195	Phosphorylation	ILQDSNDSPLAEREP EEECCCCCCCCCCCC	26.51	19664994
208	Phosphorylation	EPGEVIDSLVGKQVE CCCCHHHHHCCCEEE	17.52	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SPIN3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SPIN3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SPIN3_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of SPIN3_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.