UniProt ID | SPESP_HUMAN | |
---|---|---|
UniProt AC | Q6UW49 | |
Protein Name | Sperm equatorial segment protein 1 {ECO:0000312|HGNC:HGNC:15570} | |
Gene Name | SPESP1 {ECO:0000312|HGNC:HGNC:15570} | |
Organism | Homo sapiens (Human). | |
Sequence Length | 350 | |
Subcellular Localization | Cytoplasmic vesicle, secretory vesicle, acrosome . Small proacrosomal granules (during the Golgi phase), enlarged acrosomal vesicles (during the cap phase), acrosome (during the elongating phase), equatorial segment of the acrosome (during the matura | |
Protein Description | Involved in fertilization ability of sperm.. | |
Protein Sequence | MKPLVLLVALLLWPSSVPAYPSITVTPDEEQNLNHYIQVLENLVRSVPSGEPGREKKSNSPKHVYSIASKGSKFKELVTHGDASTENDVLTNPISEETTTFPTGGFTPEIGKKKHTESTPFWSIKPNNVSIVLHAEEPYIENEEPEPEPEPAAKQTEAPRMLPVVTESSTSPYVTSYKSPVTTLDKSTGIGISTESEDVPQLSGETAIEKPEEFGKHPESWNNDDILKKILDINSQVQQALLSDTSNPAYREDIEASKDHLKRSLALAAAAEHKLKTMYKSQLLPVGRTSNKIDDIETVINMLCNSRSKLYEYLDIKCVPPEMREKAATVFNTLKNMCRSRRVTALLKVY | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
65 | Phosphorylation | SNSPKHVYSIASKGS CCCCCHHHEHHHCCC | 8.28 | - | |
128 | N-linked_Glycosylation | FWSIKPNNVSIVLHA CEECCCCCEEEEEEE | 37.12 | UniProtKB CARBOHYD | |
168 | Phosphorylation | MLPVVTESSTSPYVT EECEEECCCCCCCCC | 29.56 | 26434552 | |
171 | Phosphorylation | VVTESSTSPYVTSYK EEECCCCCCCCCCCC | 19.04 | 26434552 | |
179 | Phosphorylation | PYVTSYKSPVTTLDK CCCCCCCCCCEEECC | 19.17 | - | |
235 | Phosphorylation | KKILDINSQVQQALL HHHHCCCHHHHHHHH | 31.87 | 18491316 | |
243 | Phosphorylation | QVQQALLSDTSNPAY HHHHHHHCCCCCHHH | 39.43 | 18491316 | |
298 | Phosphorylation | NKIDDIETVINMLCN CCHHHHHHHHHHHHC | 27.33 | 30576142 | |
306 | Phosphorylation | VINMLCNSRSKLYEY HHHHHHCCCHHHHHH | 36.61 | 20873877 | |
333 | Phosphorylation | KAATVFNTLKNMCRS HHHHHHHHHHHHHHH | 27.87 | 27251275 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SPESP_HUMAN !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SPESP_HUMAN !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SPESP_HUMAN !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
Oops, there are no PPI records of SPESP_HUMAN !! |
Kegg Disease | ||||||
---|---|---|---|---|---|---|
There are no disease associations of PTM sites. | ||||||
OMIM Disease | ||||||
There are no disease associations of PTM sites. | ||||||
Kegg Drug | ||||||
There are no disease associations of PTM sites. | ||||||
DrugBank | ||||||
There are no disease associations of PTM sites. |
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