SPESP_HUMAN - dbPTM
SPESP_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SPESP_HUMAN
UniProt AC Q6UW49
Protein Name Sperm equatorial segment protein 1 {ECO:0000312|HGNC:HGNC:15570}
Gene Name SPESP1 {ECO:0000312|HGNC:HGNC:15570}
Organism Homo sapiens (Human).
Sequence Length 350
Subcellular Localization Cytoplasmic vesicle, secretory vesicle, acrosome . Small proacrosomal granules (during the Golgi phase), enlarged acrosomal vesicles (during the cap phase), acrosome (during the elongating phase), equatorial segment of the acrosome (during the matura
Protein Description Involved in fertilization ability of sperm..
Protein Sequence MKPLVLLVALLLWPSSVPAYPSITVTPDEEQNLNHYIQVLENLVRSVPSGEPGREKKSNSPKHVYSIASKGSKFKELVTHGDASTENDVLTNPISEETTTFPTGGFTPEIGKKKHTESTPFWSIKPNNVSIVLHAEEPYIENEEPEPEPEPAAKQTEAPRMLPVVTESSTSPYVTSYKSPVTTLDKSTGIGISTESEDVPQLSGETAIEKPEEFGKHPESWNNDDILKKILDINSQVQQALLSDTSNPAYREDIEASKDHLKRSLALAAAAEHKLKTMYKSQLLPVGRTSNKIDDIETVINMLCNSRSKLYEYLDIKCVPPEMREKAATVFNTLKNMCRSRRVTALLKVY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
65PhosphorylationSNSPKHVYSIASKGS
CCCCCHHHEHHHCCC
8.28-
128N-linked_GlycosylationFWSIKPNNVSIVLHA
CEECCCCCEEEEEEE
37.12UniProtKB CARBOHYD
168PhosphorylationMLPVVTESSTSPYVT
EECEEECCCCCCCCC
29.5626434552
171PhosphorylationVVTESSTSPYVTSYK
EEECCCCCCCCCCCC
19.0426434552
179PhosphorylationPYVTSYKSPVTTLDK
CCCCCCCCCCEEECC
19.17-
235PhosphorylationKKILDINSQVQQALL
HHHHCCCHHHHHHHH
31.8718491316
243PhosphorylationQVQQALLSDTSNPAY
HHHHHHHCCCCCHHH
39.4318491316
298PhosphorylationNKIDDIETVINMLCN
CCHHHHHHHHHHHHC
27.3330576142
306PhosphorylationVINMLCNSRSKLYEY
HHHHHHCCCHHHHHH
36.6120873877
333PhosphorylationKAATVFNTLKNMCRS
HHHHHHHHHHHHHHH
27.8727251275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SPESP_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SPESP_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SPESP_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of SPESP_HUMAN !!

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SPESP_HUMAN

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Related Literatures of Post-Translational Modification

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