SPDE2_HUMAN - dbPTM
SPDE2_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SPDE2_HUMAN
UniProt AC Q495Y8
Protein Name Speedy protein E2
Gene Name SPDYE2
Organism Homo sapiens (Human).
Sequence Length 402
Subcellular Localization
Protein Description
Protein Sequence MDRTETRFRKRGQITGKITTSRQPHPQNEQSPQRSTSGYPLQEVVDDEMLGPSAPGVDPSPPCRSLGWKRKREWSDESEEEPEKELAPEPEETWVVEMLCGLKMKLKQQRVSPILPEHHKDFNSQLAPGVDPSPPHRSFCWKRKMEWWDESEESLEEEPRKVLAPEPEEIWVAEMLCGLKMKLKRRRVSLVLPEHHEAFNRLLEDPVIKRFLAWDKDLRVSDKYLLAMVIAYFSRAGFPSWQYQRIHFFLALYLANDMEEDDEDSKQNIFHFLYRKNRSRIPLLRKPWFQLGHSMNPRARKNRSRIPLLRKRRFQLYRSTNPRARKNRSRIPLLRKRRFQLYRSMNSRARKNRSQIVLFQKRRFHFFCSMSCRAWVSPEELEEIQAYDPEHWVWARDRAHLS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
6Phosphorylation--MDRTETRFRKRGQ
--CCCHHHHHHHHCC
34.2028509920
60PhosphorylationSAPGVDPSPPCRSLG
CCCCCCCCCCCHHHC
36.69-
75PhosphorylationWKRKREWSDESEEEP
CCCCCCCCCCCCCCC
27.0930622161
78PhosphorylationKREWSDESEEEPEKE
CCCCCCCCCCCCHHH
56.1330622161
133PhosphorylationLAPGVDPSPPHRSFC
CCCCCCCCCCCCCHH
46.7525693802
224PhosphorylationDLRVSDKYLLAMVIA
CCCCCHHHHHHHHHH
16.3722817900
232PhosphorylationLLAMVIAYFSRAGFP
HHHHHHHHHHHCCCC
7.3226270265
234PhosphorylationAMVIAYFSRAGFPSW
HHHHHHHHHCCCCHH
14.4526270265
243PhosphorylationAGFPSWQYQRIHFFL
CCCCHHHHHHHHHHH
8.10-
253PhosphorylationIHFFLALYLANDMEE
HHHHHHHHHHHCCCC
9.73-
344PhosphorylationRRFQLYRSMNSRARK
HHHHHHHHHHHHHHH
14.57-
354PhosphorylationSRARKNRSQIVLFQK
HHHHHCHHHEEEEEC
33.3830622161

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SPDE2_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SPDE2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SPDE2_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of SPDE2_HUMAN !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SPDE2_HUMAN

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Related Literatures of Post-Translational Modification

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