| UniProt ID | SPB1_MOUSE | |
|---|---|---|
| UniProt AC | Q9DBE9 | |
| Protein Name | pre-rRNA processing protein FTSJ3 {ECO:0000255|HAMAP-Rule:MF_03163} | |
| Gene Name | Ftsj3 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 838 | |
| Subcellular Localization | Nucleus, nucleolus . | |
| Protein Description | Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.. | |
| Protein Sequence | MGKKGKVGKSRRDKFYHLAKETGYRSRSAFKLIQLNRRFQFLQKARALLDLCAAPGGWLQVAAKFMPVSSLIVGVDLVPIKPLPNVVTLQEDITTERCRQALRKELKTWKVDVVLNDGAPNVGASWVHDAYSQAHLTLMALRLACDFLARGGCFITKVFRSRDYQPLLWIFQQLFHRVQATKPQASRHESAEIFVVCQGFLAPDKVDAKFFDPKFAFKEVEVQAKTVTELVTKKKPKAEGYAEGDLTLYHRTSVTDFLRAANPVDFLSKASEISIDDEELAQHPATTEDIRVCCQDIKVLGRKELRSLLNWRTKLRRYVAKKLKEQAKALDISLSSEEEEEGDEEEAVAETKQAPEEEEEREEEQLNRTLAEMKAQEVAELKRKKKKLLREQRKQRERVELKMDLPGVSIADEGETGMFSLRTIRGQQLLEEVTQGDMNAADTFLSDLPRDDIYVSDAEDDDDTSLESDLDPEELAGVRTHSDLKEQKYLRFTQVDDNKEEEGENPLLVPLEEKAVLQEEQASLWFSKDGFSGIEDDADEALEISQAQLLYKSRQKEQQPTDPPPPPTNLKTEKKSPQGQNEVPKETEAILGTEAVTDPGGEERGNSSDSDSSSSEDEDSWKVSRGVKRGRGSKADEDGFEVVPIQDPVKYRILDPEGLALGAVIASSKKAKRDLIDNSFNRYAFNEEEGELPEWFAQEEKQHRIRQLPVDKKEVEHYRKRWREINARPIKKVAEAKARKKRRVLKKLEQTKKKAEAVVNTVDISEREKVAQLRSLYKKAGLGKEKRQVTYVVAKKGVGRKVRRPAGVKGHFKVVDSRMKKDQRAQQRKEQKKKHKRK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 157 | Acetylation | RGGCFITKVFRSRDY HCCCEEEEHHHCCCC | 22826441 | ||
| 214 | Ubiquitination | DAKFFDPKFAFKEVE CCCCCCCCCCCEEEE | - | ||
| 233 | Acetylation | TVTELVTKKKPKAEG EHHHHHHCCCCCCCC | 23806337 | ||
| 271 | Phosphorylation | VDFLSKASEISIDDE HHHHHHCCCCCCCHH | 26745281 | ||
| 274 | Phosphorylation | LSKASEISIDDEELA HHHCCCCCCCHHHHH | 26745281 | ||
| 333 | Phosphorylation | QAKALDISLSSEEEE HHHHHCCCCCCHHHH | 21082442 | ||
| 335 | Phosphorylation | KALDISLSSEEEEEG HHHCCCCCCHHHHCC | 27087446 | ||
| 336 | Phosphorylation | ALDISLSSEEEEEGD HHCCCCCCHHHHCCC | 27087446 | ||
| 351 | Phosphorylation | EEEAVAETKQAPEEE HHHHHHHHHCCCHHH | 25619855 | ||
| 390 | Citrullination | RKKKKLLREQRKQRE HHHHHHHHHHHHHHH | - | ||
| 390 | Citrullination | RKKKKLLREQRKQRE HHHHHHHHHHHHHHH | 24463520 | ||
| 454 | Phosphorylation | DLPRDDIYVSDAEDD CCCCCCEEECCCCCC | 25159016 | ||
| 456 | Phosphorylation | PRDDIYVSDAEDDDD CCCCEEECCCCCCCC | 21659605 | ||
| 464 | Phosphorylation | DAEDDDDTSLESDLD CCCCCCCCCCCCCCC | 21659605 | ||
| 465 | Phosphorylation | AEDDDDTSLESDLDP CCCCCCCCCCCCCCH | 21659605 | ||
| 468 | Phosphorylation | DDDTSLESDLDPEEL CCCCCCCCCCCHHHH | 21659605 | ||
| 532 | Phosphorylation | WFSKDGFSGIEDDAD HCCCCCCCCCCCCHH | 23984901 | ||
| 545 | Phosphorylation | ADEALEISQAQLLYK HHHHHHHHHHHHHHH | - | ||
| 576 | Phosphorylation | NLKTEKKSPQGQNEV CCCCCCCCCCCCCCC | 26824392 | ||
| 593 | Phosphorylation | ETEAILGTEAVTDPG HHHHHHCCEEECCCC | 28066266 | ||
| 597 | Phosphorylation | ILGTEAVTDPGGEER HHCCEEECCCCCCCC | 28066266 | ||
| 633 | Phosphorylation | GVKRGRGSKADEDGF CHHCCCCCCCCCCCC | 25159016 | ||
| 634 | Acetylation | VKRGRGSKADEDGFE HHCCCCCCCCCCCCE | 23806337 | ||
| 650 | Ubiquitination | VPIQDPVKYRILDPE EECCCCCEEEEECHH | - | ||
| 667 | Phosphorylation | ALGAVIASSKKAKRD HHHHHHHCCHHHHHH | 26745281 | ||
| 668 | Phosphorylation | LGAVIASSKKAKRDL HHHHHHCCHHHHHHH | 26745281 | ||
| 669 | Ubiquitination | GAVIASSKKAKRDLI HHHHHCCHHHHHHHH | - | ||
| 679 | Phosphorylation | KRDLIDNSFNRYAFN HHHHHHCCCHHCCCC | 25168779 | ||
| 683 | Phosphorylation | IDNSFNRYAFNEEEG HHCCCHHCCCCCCCC | 26745281 | ||
| 737 | Acetylation | IKKVAEAKARKKRRV HHHHHHHHHHHHHHH | 2395161 | ||
| 752 | Acetylation | LKKLEQTKKKAEAVV HHHHHHHHHHHHHHH | 7714481 | ||
| 753 | Acetylation | KKLEQTKKKAEAVVN HHHHHHHHHHHHHHH | 7714491 | ||
| 774 | Citrullination | REKVAQLRSLYKKAG HHHHHHHHHHHHHCC | 24463520 | ||
| 774 | Citrullination | REKVAQLRSLYKKAG HHHHHHHHHHHHHCC | - | ||
| 779 | Acetylation | QLRSLYKKAGLGKEK HHHHHHHHCCCCCCH | 7611995 | ||
| 784 | Acetylation | YKKAGLGKEKRQVTY HHHCCCCCCHHEEEE | 7296893 | ||
| 809 | Ubiquitination | VRRPAGVKGHFKVVD CCCCCCCCCCHHHCC | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SPB1_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SPB1_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SPB1_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of SPB1_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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