| UniProt ID | SPART_MOUSE | |
|---|---|---|
| UniProt AC | Q8R1X6 | |
| Protein Name | Spartin {ECO:0000305} | |
| Gene Name | Spart {ECO:0000250|UniProtKB:Q8N0X7} | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 671 | |
| Subcellular Localization | Cytoplasm . Midbody . Transiently associated with endosomes. Colocalized with IST1 to the ends of Flemming bodies during cytokinesis. | |
| Protein Description | May be implicated in endosomal trafficking, or microtubule dynamics, or both. Participates in cytokinesis.. | |
| Protein Sequence | MEREPENGEPAEIKIIKEAYEKAFMFVNKGLNTDELGQKEEAKNYYKQGIGHLLRGISIAAAEPGHTGPAWEAARQMQQKMKETLQNVRTRLEILEKGLATSLRNDLQDVPKLYPEFPPKDACKKSPEQESVSTAPQRAEVDGSASAACAGPSGAPSALPVPSPSCPAEAPPAYSPQAAEGHYTVSYGTDSGEFSSVGEDFYRNRSQPPPLETLGLDADELILIPNGVQIFFVNPAGEVSAPSYPGYLRIVRFLDNSLDTVLNRPPGFLQVCDWLYPLVPDRSPVLKCTVGAYMFPDTMLQAAGCFVGVVLSSELPEDDRELFEDLLRQMSDLRLQANWNREEDEFQIPGRSSHPSEPPKEASGTDVRQSSSSGSSIDQGSKDARHKGKRGKKTKDSSEEVNLSQIVPCEPSSEEKSKELPEWSEKVAHNILSGASWVSWGLVKGAEFTGKAIQKGASKLRERIQPEEKPVEVSPAVTRGLYIAKQATGGAAKVSQLLVDGVCTVANCVGKELAPHVKKHGSKLVPESLKRDKDGKSALDGAMVVAASSVQGFSTVWQGLECAAKCIVNNVSAETVQTVRYKYGHNAGEATHNAVDSAINVGLTAYNIDNIGIKAMVKKTAKQTGHTLLEDYQIVERPQRESQGGATSTEGRRDIGKQVEEEKPGAGKKDK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MEREPENG -------CCCCCCCC | - | ||
| 47 | Ubiquitination | EEAKNYYKQGIGHLL HHHHHHHHHHHHHHH | - | ||
| 58 | Phosphorylation | GHLLRGISIAAAEPG HHHHHHCCEEECCCC | 29514104 | ||
| 82 | Ubiquitination | RQMQQKMKETLQNVR HHHHHHHHHHHHHHH | - | ||
| 101 | Phosphorylation | ILEKGLATSLRNDLQ HHHHHHHHHHHHHHH | 26060331 | ||
| 102 | Phosphorylation | LEKGLATSLRNDLQD HHHHHHHHHHHHHHH | 26060331 | ||
| 126 | Phosphorylation | PKDACKKSPEQESVS CHHHCCCCCCCCCCC | 25521595 | ||
| 131 | Phosphorylation | KKSPEQESVSTAPQR CCCCCCCCCCCCCCC | 25619855 | ||
| 133 | Phosphorylation | SPEQESVSTAPQRAE CCCCCCCCCCCCCEE | 25619855 | ||
| 134 | Phosphorylation | PEQESVSTAPQRAEV CCCCCCCCCCCCEEC | 25619855 | ||
| 287 | Ubiquitination | PDRSPVLKCTVGAYM CCCCCCEEECEECCC | - | ||
| 337 (in isoform 2) | Phosphorylation | - | 29899451 | ||
| 360 | Ubiquitination | SHPSEPPKEASGTDV CCCCCCCCCCCCCCC | - | ||
| 363 | Phosphorylation | SEPPKEASGTDVRQS CCCCCCCCCCCCCCC | 22871156 | ||
| 365 | Phosphorylation | PPKEASGTDVRQSSS CCCCCCCCCCCCCCC | 22871156 | ||
| 375 | Phosphorylation | RQSSSSGSSIDQGSK CCCCCCCCCCCCCCC | 29899451 | ||
| 382 | Ubiquitination | SSIDQGSKDARHKGK CCCCCCCCCHHHCCC | - | ||
| 395 | Ubiquitination | GKRGKKTKDSSEEVN CCCCCCCCCCCCCCC | - | ||
| 418 | Ubiquitination | PSSEEKSKELPEWSE CCCHHHHHCCCHHHH | - | ||
| 444 | Ubiquitination | WVSWGLVKGAEFTGK HHHHHHCCCCHHHHH | - | ||
| 451 | Ubiquitination | KGAEFTGKAIQKGAS CCCHHHHHHHHHHHH | - | ||
| 469 | Ubiquitination | ERIQPEEKPVEVSPA HHCCCCCCCCCCCHH | - | ||
| 474 | Phosphorylation | EEKPVEVSPAVTRGL CCCCCCCCHHHHHCE | 26824392 | ||
| 478 | Phosphorylation | VEVSPAVTRGLYIAK CCCCHHHHHCEEEEH | 28066266 | ||
| 478 | O-linked_Glycosylation | VEVSPAVTRGLYIAK CCCCHHHHHCEEEEH | 30059200 | ||
| 482 | Phosphorylation | PAVTRGLYIAKQATG HHHHHCEEEEHHHCC | 29514104 | ||
| 485 | Ubiquitination | TRGLYIAKQATGGAA HHCEEEEHHHCCCCC | - | ||
| 493 | Ubiquitination | QATGGAAKVSQLLVD HHCCCCCHHHHHHHC | - | ||
| 511 | Ubiquitination | TVANCVGKELAPHVK HHHHHCCHHHHHHHH | - | ||
| 528 | Phosphorylation | GSKLVPESLKRDKDG CCCCCCHHHCCCCCC | 29514104 | ||
| 530 | Ubiquitination | KLVPESLKRDKDGKS CCCCHHHCCCCCCCC | - | ||
| 533 | Ubiquitination | PESLKRDKDGKSALD CHHHCCCCCCCCHHC | - | ||
| 622 | Ubiquitination | AMVKKTAKQTGHTLL HHHHHHHHHHCCCHH | - | ||
| 632 | Phosphorylation | GHTLLEDYQIVERPQ CCCHHHHCEEEECCC | 29514104 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SPART_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SPART_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SPART_MOUSE !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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