dbPTM

SPART_BOVIN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SPART_BOVIN
UniProt AC	A0JNJ3
Protein Name	Spartin {ECO:0000305}
Gene Name	SPART {ECO:0000250\|UniProtKB:Q8N0X7}
Organism	Bos taurus (Bovine).
Sequence Length	668
Subcellular Localization	Cytoplasm . Midbody . Transiently associated with endosomes. Colocalized with IST1 to the ends of Flemming bodies during cytokinesis.
Protein Description	May be implicated in endosomal trafficking, or microtubule dynamics, or both. Participates in cytokinesis..
Protein Sequence	MEQGPQDGEPIEIKIIKEAYKKAFVFVNKGLNTDELGQKEEAKNYYKQGIGHLLRGISISSTDPEYTGPEWESARQMQQKMKETLQNVRTRLEILEKGLATSLRNDLQEVPKLYPEFPPKDMSEKSPEPQSLSSLPQHSEVNGSTSTASAESSSTPTTLSLPCQSHPSEAPPAYTPQAAEGHYTVSYGTESGEFSSVGENFYRNHSQPPPLETLGLDADELILIPNGVQIFFVNPAGEVSAPSYPGYLRIVRFLDNSLDTFLNRPPGFLQVCDWLYPLVPDRSPVLKCTVGAYMFPDTMLQASGCFVGVVLSSELPEDDRELFEDLLRQMSDLRLQTNWDRAEGENEFQIPGISGSASDQLKEASGTDVRQLDPSSKDVRQKGKRGKKTKGTSSEEVNLSHIVPCEPVSEEKAKELPEWSEKVAHNILSGASWVSWGLVKGAEFTGKAIQKGASKLRERIQPEEKPVEVSPAVTKGLYMAKQATGGAAKVSQFLVDGVCTVANCVGKELAPHVKKHGSKLVPESLKKDRNGKSTLDGAMVVAASSVQGFSTVWQGLECAAKCIVNNVSAETVQTVRYKYGHTAGEATHNAVDSAINVGVTAYNIDNIGIKAMVKKTAKQTGHTLLEDYKIIDNSKGENPGGGASANLKGEKDEQKEGPEKNGAKKKDK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
1	Acetylation	-------MEQGPQDG -------CCCCCCCC	-
126	Phosphorylation	PKDMSEKSPEPQSLS CCCCCCCCCCCCCHH	-
470	Phosphorylation	EEKPVEVSPAVTKGL CCCCCCCCHHHHHHH	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SPART_BOVIN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SPART_BOVIN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SPART_BOVIN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SPART_BOVIN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SPART_BOVIN

Related Literatures of Post-Translational Modification