SPA3C_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SPA3C_MOUSE
• UniProt AC: P29621
• Protein Name: Serine protease inhibitor A3C
• Gene Name: Serpina3c
• Organism: Mus musculus (Mouse).
• Sequence Length: 417
• Subcellular Localization: Secreted.
• Protein Sequence: MAFIVALGLVITGICPGVLCFPDGTLERDTLFHKDKENGTQLDSLTLASINTDFAFSLYKKLALKNPDTNIVFSPLSISAALAIVSLGAKGNTLEEILEGLNFNLTETPEADIHQGFGHLLQRLSHPGEQVQISTGSALFVEKHLQILAEFQEKARALYQAEAFTADFQQPLEATKLINDYVSNQTQRKIKGLISDLDTDTLMVLVNYIYFKGKWKMPFNPRDTFESEFYLDVKRSVKVPMMKIKTLTTPYFRDEELSCTVVELKYKGNASALFILPDQGRMQQVEASLQPETLRKWKNSLRPRKMGELYLPKFSISTDYSLKNILPELGIKEIFSKQADLSGITGTKDLIVSQMVHKAVLDVAETGTEGVAATGVNFRILSRRTSLWFNRTFLMVISHTDVQTTLFIAKITHPKRA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
38	N-linked_Glycosylation	LFHKDKENGTQLDSL CEEECCCCCCCCEEE	65.63	-
93	Phosphorylation	SLGAKGNTLEEILEG HCCCCCCCHHHHHHH	44.19	-
104	N-linked_Glycosylation	ILEGLNFNLTETPEA HHHHCCCCCCCCCCC	45.00	-
125	Phosphorylation	GHLLQRLSHPGEQVQ HHHHHHHCCCCCEEE	29.80	28576409
184	N-linked_Glycosylation	LINDYVSNQTQRKIK HHHHHHCHHHHHHHH	38.58	-
236	Phosphorylation	FYLDVKRSVKVPMMK EEEEEHHCCCCCEEE	22.14	-
266	Phosphorylation	CTVVELKYKGNASAL EEEEEEEECCCEEEE	36.43	29895711
269	N-linked_Glycosylation	VELKYKGNASALFIL EEEEECCCEEEEEEE	26.94	-
271	Phosphorylation	LKYKGNASALFILPD EEECCCEEEEEEECC	29.51	29895711
300	Phosphorylation	TLRKWKNSLRPRKMG HHHHHHHHCCCCCCC	23.25	26060331
337	Ubiquitination	GIKEIFSKQADLSGI CHHHHHCCCCCCCCC	38.46	27667366
356	Ubiquitination	DLIVSQMVHKAVLDV HHHHHHHHHHHHHHH	3.04	27667366
368	Phosphorylation	LDVAETGTEGVAATG HHHHHHCCCCCCCCC	36.67	23882026
382	Phosphorylation	GVNFRILSRRTSLWF CCCEEEEECCCCEEE	19.83	23882026
390	N-linked_Glycosylation	RRTSLWFNRTFLMVI CCCCEEECCEEEEEE	30.42	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SPA3C_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SPA3C_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SPA3C_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SPA3C_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.